关键词: 铜绿假单胞菌, 感染, 耐药性

Abstract:

Objective To analyze the source of Pseudomonas aeruginosa and the drug resistance status for different ages,and to provide a reference for clinical anti-infection treatment. Methods Identification and drug susceptibility analysis for 3 726 clinically isolated bacteria from June 2017 to February 2018 were performed. The patients for the 3 726 clinically isolated bacteria were classified into ≤14-year-old,15-60-year-old and >60-year-old groups. Results A total of 354 isolates of Pseudomonas aeruginosa were isolated from the 3 726 clinical specimens,and the isolation rate was 9.5%. The main types of clinical specimens were sputum（59.9%）,drainage fluid（13.3%）,urine（10.7%）,throat swab（6.2%）,blood（5.1%） and secreta（1.4%）. The departments with high isolation rates were intensive care unit（ICU）（19.4%）,emergency（18.4%） and respiratory medicine（12.7%）. Pseudomonas aeruginosa isolated from ≤14-year-old group were sensitive to amikacin,cefepime and tobramycin. The drug resistance rates of 15-60-year-old and >60-year-old groups were similar,and the drug resistance rates to amikacin were the lowest（8.8% and 11.7%,respectively）,followed by tobramycin,gentamicin and cefepime. Conclusions Pseudomonas aeruginosa are isolated from sputum mainly. The drug resistance rates to amikacin and tobramycin are low. Clinic should choose rational antibiotics according to the results of drug susceptibility analysis.

Key words: Pseudomonas aeruginosa, Infection, Drug resistance