关键词: 宫颈癌, 液基细胞学, 人乳头瘤病毒, 外来务工人员

Abstract: Objective　To investigate the prevalence of cervical diseases and high-risk human papillomavirus (HR-HPV) infection in migrant female workers in Fengxian District，Shanghai.  Methods　The results of liquid-based cytology and HR-HPV detection of 708 migrant female workers seeking medical advice for possible cervical diseases in Fengxian District，Shanghai were analyzed retrospectively. The results of biopsy and loop electrosurgical excisional procedure (LEEP) from a part of these patients were also analyzed.  Results　Among these migrant female workers，the prevalences of atypical squamous cell (ASC)，low-grade squamous intraepithelial lesion (LSIL) and high-grade squamous intraepithelial lesion (HSIL) were 31.6%，23.2% and 11.9%，respectively. The prevalence of HR-HPV was 68.4%. With the increase of age，the prevalences of LSIL and HR-HPV decreased，but the prevalence of HSIL increased. Cervical intraepithelial neoplasia or worse (CIN2+) results were found by biopsy in 35.7% of HR-HPV positive ASC patients and 37.8% of HR-HPV positive LSIL patients，respectively. Among HSIL patients，85.7% were CIN2+ by biopsy or LEEP.  Conclusions　The prevalence of cervical diseases is high among migrant female workers in Fengxian District，Shanghai. Some of them have high-grade lesions.

Key words: Cervical carcinoma, Liquid-based cytology, Human papillomavirus, Migrant worker