1 |
FUENTES M,HERMOSILLA G,ALBURQUENQUE C,et al.Characterization of azole resistance mechanisms in Chilean clinical isolates of Candida albicans[J]. Rev Chilena Infectol, 2014,31(5):511-517.
|
2 |
ST GEORGIEV V.Membrane transporters and antifungal drug resistance[J]. Curr Drug Targets,2000,1(3):261-284.
|
3 |
MARR KA,LYONS CN,HA K,et al.Inducible azole resistance associated with a heterogeneous phenotype in Candida albicans[J]. Antimicrob Agents Chemother,2001,45(1):52-59.
|
4 |
LIU TT,ZNAIDI S,BARKER KS,et al.Genome-wide expression and location analyses of the Candida albicans Tac1p regulon[J]. Eukaryot Cell,2007,6(11):2122-2138.
|
5 |
MORSCHHÄUSER J. Regulation of multidrug resistance in pathogenic fungi[J]. Fungal Genet Biol,2010,47(2):94-106.
|
6 |
COSTE AT,CRITTIN J,BAUSER C,et al.Functional analysis of cis- and trans-acting elements of the Candida albicans CDR2 promoter with a novel promoter reporter system[J]. Eukaryot Cell,2009,8(8):1250-1267.
|
7 |
MORIO F,PAGNIEZ F,BESSE M,et al.Deciphering azole resistance mechanisms with a focus on transcription factor-encoding genes TAC1,MRR1 and UPC2 in a set of fluconazole-resistant clinical isolates of Candida albicans[J]. Int J Antimicrob Agents,2013,42(5):410-415.
|
8 |
JENSEN RH,ASTVAD KM,SILVA LV,et al.Stepwise emergence of azole,echinocandin and amphotericin B multidrug resistance in vivo in Candida albicans orchestrated by multiple genetic alterations[J]. J Antimicrob Chemother,2015,70(9):2551-2555.
|
9 |
SCHILLIG R,MORSCHHÄUSER J. Analysis of a fungus-specific transcription factor family,the Candida albicans zinc cluster proteins,by artificial activation[J]. Mol Microbiol,2013,89(5):1003-1017.
|
10 |
WANG Y,LIU J,SHI C,et al.Mutations in transcription factor Mrr2p contribute to fluconazole resistance in clinical isolates of Candida albicans[J]. Int J Antimicrob Agents,2015,46(5):552-559.
|
11 |
DUNKEL N,BLASS J,ROGERS PD,et al.Mutations in the multi-drug resistance regulator MRR1,followed by loss of heterozygosity,are the main cause of MDR1 overexpression in fluconazole-resistant Candida albicans strains[J]. Mol Microbiol,2008,69(4):827-840.
|
12 |
MORIO F,PAGNIEZ F,BESSE M,et al.Deciphering azole resistance mechanisms with a focus on transcription factor-encoding genes TAC1,MRR1 and UPC2 in a set of fluconazole-resistant clinical isolates of Candida albicans[J]. Int J Antimicrob Agents,2013,42(5):410-415.
|
13 |
CHEN CG,YANG YL,TSENG KY,et al.Rep1p negatively regulating MDR1 efflux pump involved in drug resistance in Candida albicans[J]. Fungal Genet Biol,2009,46(9):714-720.
|
14 |
LO HJ,TSENG KY,KAO YY,et al.Cph1p negatively regulates MDR1 involved in drug resistance in Candida albicans[J]. Int J Antimicrob Agents,2015,45(6):617-621.
|
15 |
CALABRESE D,BILLE J,SANGLARD D.A novel multidrug efflux transporter gene of the major facilitator superfamily from Candida albicans (FLU1) conferring resistance to fluconazole[J]. Microbiology,2000,146( Pt 11):2743-2754.
|
16 |
XU Y,SHENG F,ZHAO J,et al.ERG11 mutations and expression of resistance genes in fluconazole-resistant Candida albicans isolates[J]. Arch Microbiol,2015,197(9):1087-1093.
|
17 |
ZHANG JY,LIU JH,LIU FD,et al.Vulvovaginal candidiasis:species distribution,fluconazole resistance and drug efflux pump gene overexpression[J]. Mycoses,2014,57(10):584-591.
|
18 |
SANGLARD D,ISCHER F,PARKINSON T,et al.Candida albicans mutations in the ergosterol biosynthetic pathway and resistance to several antifungal agents[J]. Antimicrob Agents Chemother,2003,47(8):2404-2412.
|
19 |
MORIO F,PAGNIEZ F,LACROIX C,et al.Amino acid substitutions in the Candida albicans sterol Δ5,6-desaturase (Erg3p) confer azole resistance:characterization of two novel mutants with impaired virulence[J]. J Antimicrob Chemother,2012,67(9):2131-2138.
|
20 |
MARTEL CM,PARKER JE,BADER O,et al.Identification and characterization of four azole-resistant erg3 mutants of Candida albicans[J]. Antimicrob Agents Chemother,2010,54(11):4527-4533.
|
21 |
陈晋宇,冯文莉,杨静,等. 临床白念珠菌耐药性与ERG3基因突变及表达的关系[J]. 国际医药卫生导报,2014,20(13):1838-1844.
|
22 |
LIU JY,SHI C,WANG Y,et al.Mechanisms of azole resistance in Candida albicans clinical isolates from Shanghai,China[J]. Res Microbiol,2015,166(3):153-161.
|
23 |
SANGLARD D,ISCHER F,KOYMANS L,et al.Amino acid substitutions in the cytochrome P-450 lanosterol 14alpha-demethylase(CYP51A1) from azole-resistant Candida albicans clinical isolates contribute to resistance to azole antifungal agents[J]. Antimicrob Agents Chemother,1998,42(2):241-253.
|
24 |
TEYMURI M,MAMISHI S,POURAKBARI B,et al.Investigation of ERG11 gene expression among fluconazole-resistant Candida albicans: first report from an Iranian referral paediatric hospital[J]. Br J Biomed Sci,2015,72(1):28-31.
|
25 |
MORIO F,LOGE C,BESSE B,et al.Screening for amino acid substitutions in the Candida albicans Erg11 protein of azole-susceptible and azole-resistant clinical isolates:new substitutions and a review of the literature[J]. Diagn Microbiol Infect Dis,2010,66(4):373-384.
|
26 |
FLOWERS SA,COLON B,WHALEY SG,et al.Contribution of clinically derived mutations in ERG11 to azole resistance in Candida albicans[J]. Antimicrob Agents Chemother,2015,59(1):450-460.
|
27 |
刘锦燕,倪培华,史册,等. 白念珠菌14-α脱甲基酶 K143Q 氨基酸置换与氟康唑耐药形成的相关性研究[J]. 检验医学,2014,29(7):750-754.
|
28 |
OLIVER BG,SONG JL,CHOINIERE JH,et al.cis-Acting elements within the Candida albicans ERG11 promoter mediate the azole response through transcription factor Upc2p[J]. Eukaryot Cell,2007,6(12):2231-2239.
|
29 |
MACPHERSON S,AKACHE B,WEBER S,et al.Candida albicans zinc cluster protein Upc2p confers resistance to antifungal drugs and is an activator of ergosterol biosynthetic genes[J]. Antimicrob Agents Chemother,2005,49(5):1745-1752.
|
30 |
FLOWERS SA,BARKER KS,BERKOW EL,et al.Gain-of-function mutations in UPC2 are a frequent cause of ERG11 upregulation in azole-resistant clinical isolates of Candida albicans[J]. Eukaryot Cell,2012,11(10):1289-1299.
|
31 |
NOBILE CJ,NETT JE,ANDES DR,et al.Function of Candida albicans adhesin Hwp1 in biofilm formation[J]. Eukaryot Cell,2006,5(10):1604-1610.
|
32 |
FANNING S,XU W,SOLIS N,et al.Divergent targets of Candida albicans biofilm regulator Bcr1 in vitro and in vivo[J]. Eukaryot Cell,2012,11(7):896-904.
|
33 |
CHEN HF,LAN CY.Role of SFP1 in the regulation of Candida albicans biofilm formation[J]. PLoS One,2015,10(6):e129903.
|
34 |
DESAI JV,MITCHELL AP.Microbial biofilms:Candida albicans biofilm development and its genetic control[M]. 2nd ed. Washington DC:ASM Science,2015:99-110.
|
35 |
SCHNEIDER S,MORSCHHÄUSER J. Induction of Candida albicans drug resistance genes by hybrid zinc cluster transcription factors[J]. Antimicrob Agents Chemother,2015,59(1):558-569.
|