Hcy和RDW CV联合检测在急性心肌梗死中的应用价值探讨

doi:10.3969/j.issn.1673-8640.2014.10.001

检验医学 ›› 2014, Vol. 29 ›› Issue (10): 989-991.DOI: 10.3969/j.issn.1673-8640.2014.10.001

• 临床应用研究·论著 • 下一篇

Hcy和RDW CV联合检测在急性心肌梗死中的应用价值探讨

刘艺军¹, 刘洪亮², 徐红¹

1.涟水县人民医院检验科, 江苏涟水 223400;
2.涟水县人民医院心内科, 江苏涟水 223400

收稿日期:2014-01-07 出版日期:2014-10-30 发布日期:2014-10-22
作者简介:刘艺军,男,1963年生,学士,副主任技师,主要从事血液学检验工作。
基金资助:
选取2012年7月至2013年7月涟水县人民医院心血管内科收治的AMI患者55例,所有病例均经冠状动脉造影(CAG)确诊,诊断标准符合2007年欧洲心脏病学会/美国心脏协会/美国心脏病学会基金会/世界心脏病联盟(ESC/AHA/AcCF/WHF)颁布的关于“急性心肌梗死”诊断和治疗指南; 收集同期涟水县人民医院呼吸科收治的60例肺炎患者和涟水县人民医院体检中心提供的60名健康体检者(正常对照组); AMI组、肺炎组和正常对照组在年龄、性别等方面具有可比性,差异无统计学意义(>0.05)

Investigation on the application significance on the combined detection of Hcy and RDW CV in the diagnosis of acute myocardial infarction

LIU Yijun¹, LIU Hongliang², XU Hong

1.Department of Clinical Laboratory, Lianshui People's Hospital, Jiangsu Lianshui 223400, China;
2.Department of Cardiology, Lianshui People's Hospital, Jiangsu Lianshui 223400, China

Received:2014-01-07 Online:2014-10-30 Published:2014-10-22

摘要/Abstract

摘要： 目的探讨同型半胱氨酸(Hcy)和红细胞体积分布宽度变异系数(RDW CV)联合检测对急性心肌梗死(AMI)诊断的临床价值。方法检测55例AMI患者、60例肺炎患者和60名健康体检者(正常对照组)的Hcy浓度和RDW CV水平,并对结果进行比较分析。结果AMI组Hcy和RDW CV均明显高于肺炎组和正常对照组(P<0.05);联合检测Hcy和RDW CV对AMI诊断的敏感性为92.0%、特异性为86.1%,明显高于Hcy和RDW CV单项检测的敏感性(82.6%、72.8%) 和特异性(80.0%、75.3%)(P<0.05)。结论联合检测血Hcy浓度和RDW CV水平可明显提高AMI诊断的敏感性和特异性。

关键词: 同型半胱氨酸, 红细胞体积分布宽度变异系数, 急性心肌梗死, 联合检测, 敏感性, 特异性

Abstract: Objective To investigate the clinical significance of the homocysteine (Hcy) and red blood cell distribution width coefficient of variation (RDW CV) combined detection in the diagnosis of acute myocardial infarction (AMI). Methods A total of 55 patients with AMI and 60 patients with pneumonia were enrolled, and 60 healthy subjects were enrolled as control group. The levels of Hcy and RDW CV were determined, and the results were compared. Resutls In AMI group, Hcy and RDW CV were significantly higher than those of pneumonia and control groups (P<0.05). The sensitivity of the combined detection of Hcy and RDW CV in the diagnosis of AMI was 92.0%, the specificity was 86.1%, which were higher than those of the single detections of Hcy and RDW CV (82.6%, 72.8% and 80.0%, 75.3%) (P<0 05). Conclusions The combined detection of Hcy and RDW CV can significantly improve the sensitivity and specificity in the diagnosis of AMI.

Key words: Homocysteine, Red blood cell distribution width coefficient of variation, Acute myocardial infarction, Combined detection, Sensitivity, Specificity

中图分类号:

R446.11

刘艺军, 刘洪亮, 徐红. Hcy和RDW CV联合检测在急性心肌梗死中的应用价值探讨[J]. 检验医学, 2014, 29(10): 989-991.

LIU Yijun, LIU Hongliang, XU Hong. Investigation on the application significance on the combined detection of Hcy and RDW CV in the diagnosis of acute myocardial infarction[J]. , 2014, 29(10): 989-991.

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Hcy和RDW CV联合检测在急性心肌梗死中的应用价值探讨

Investigation on the application significance on the combined detection of Hcy and RDW CV in the diagnosis of acute myocardial infarction

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