关键词: 凝血酶原时间, 活化部分凝血活酶时间, 纤维蛋白原, 比对实验, 凝血分析仪

Abstract: Objective To study the comparability of the results between SYSMEX automatic coagulation analyzer CA1500 (CA1500) and SYSMEX automatic coagulation analyzer CA7000(CA7000) coagulation analyzers. Methods Activated partial thromboplastin time (APTT), prothrombin time (PT) and fibrinogen(FIB) were detected by CA7000 (comparison method, X) and CA1500 (experimental method, Y) in 60 serum samples. The results were analyzed by t test and regression analysis. Clinical acceptability was evaluated by systematic error at medical determining level. Results There was no statistical significance between the results of PT and FIB by CA1500 and CA7000(P>0.05), and there was statistical significance between the results of APTT by CA7000 and CA1500(P<0.05). The results of APTT, PT and FIB by CA1500 were consistent with those by CA7000 according to the results of regression analysis. The systematic errors were within the 1/2 allowable error of the Clinical Laboratory Improvement Amendment 88 (CLIA'88). Conclusions The different coagulation analyzers in the same laboratory should be conducted periodically comparative experiments to ensure the comparability between test results.

Key words: Prothrombin time, Activated partial thromboplastin time, Fibrinogen, Comparison test, Coagulation analyzer