检验医学 ›› 2014, Vol. 29 ›› Issue (5): 409-413.DOI: 10.3969/j.issn.1673-8640.2014.05.001

• 肿瘤相关基因专题 •    下一篇

从“人类基因组计划”到“癌症基因组图谱计划”, 你准备好了吗?

朱玉胜   

  1. 美国南卡罗来纳医科大学临床化学与毒理学室, 查尔斯顿 29425, 美国
  • 收稿日期:2014-04-27 出版日期:2014-05-30 发布日期:2014-05-27

the Human Genome Project to the Cancer Genome Atlas, Are You Ready?

ZHU Yusheng   

  1. Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC 29425, USA
  • Received:2014-04-27 Online:2014-05-30 Published:2014-05-27

摘要:

在过去的十年里, 由于在肿瘤分子生物学研究所取得的突破, 人类在肿瘤发生机制、预防、诊断、治疗上的认识有了巨大的进步。本述评介绍了发表于这期“肿瘤相关基因”专题的综述及研究论文的特点。这些文章给我们的读者提供了癌症研究领域中与人类癌症基因组、基因多态性以及微小RNA有关的最新信息。我们希望这些新信息能推动更多的有关肿瘤相关基因的研究, 并且促进肿瘤相关基因检测在检验医学领域得到更多的临床应用。

关键词: 肿瘤, 基因组, 单核苷酸多态性, 微小RNA

Abstract:

In the last decade, enormous progress has been made in the understanding of mechanism of tumorigenesis as well as in prevention, diagnosis and treatment of tumor because of many breakthroughs in tumor molecular biology research. This editorial introduces the review and original research papers published in this special issue of "Tumor-associated Genes". These articles provide our readers with up-to-date information on human cancer genome, genetic polymorphisms and miRNAs in the field of cancer research. We hope that the new information promotes more studies on tumor-associated genes and more clinical applications of tumor-associated gene tests in the field of laboratory medicine.

Key words: Tumor, Genomics, Single nucleotide polymorphisms, MicroRNA

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