D-dimer,fibrinogen and transferrin for rheumatoid arthritis

doi:10.3969/j.issn.1673-8640.2017.010.011

Abstract

Abstract:

Objective To investigate the roles of plasma D-dimer（DD）,transferrin（Tf）,erythrocyte sedimentation rate（ESR） and fibrinogen（Fg） for rheumatoid arthritis（RA）. Methods A total of 95 patients with RA were enrolled,and 90 healthy subjects were enrolled as healthy control group. Plasma DD,Fg,hemoglobin（Hb）,platelet（PLT）,C-reactive protein（CRP）,ESR and Tf were determined. Results In RA group,DD,CRP,ESR,Fg and PLT were higher than those in healthy control group（P<0.01）,while Hb and Tf were lower（P<0.01）. Correlation analysis showed that the increasing of DD,PLT and Fg in RA group was positively correlated with 28-joint disease activity score（DAS28）（r=0.54,0.45 and 0.42,P<0.05）,and Tf was correlated negatively with DAS28（r = -0.29,P<0.01）. Conclusions DD,Tf,PLT and Fg may be used as indicators for RA disease activity assessment.

Key words: D-dimer, Fibrinogen, Transferrin, Rheumatoid arthritis, 28-Joint disease activity score

CLC Number:

R446.1

ZENG Huiqiong, FU Zhongchao, HUANG Xinmin, YIN Zhihua, YE Zhizhong. D-dimer,fibrinogen and transferrin for rheumatoid arthritis[J]. Laboratory Medicine, 2017, 32(10): 883-885.

Figures/Tables 1

References 13

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组别	例数	ESR（mm/h）	CRP（mg/L）	Tf（g/L）	Fg（g/L）	DD（μg/L）	PLT（×10⁹/L）	Hb（g/L）
RA组	95	71.60±10.60^**	62.50±15.80^**	1.35±0.63^**	3.71±0.96^*	522.20±79.20^**	374.50±69.50^**	85.90±8.20^**
活动期组	50	90.44±11.82^##	57.15±22.91^#	0.84±0.17^##	4.35±1.69^#	965.12±29.68^##	477.23±6.37^##	67.56±9.45^##
稳定期组	45	32.87±10.71	26.52±3.40	1.77±0.46	3.02±0.45	167.45±10.22	226.10±4.99	101.68±14.65
正常对照组	90	12.50±5.90	8.40±0.78	2.64±0.88	1.99±1.01	93.80±5.70	151.30±33.90	108.60±13.50

组别	例数	ESR（mm/h）	CRP（mg/L）	Tf（g/L）	Fg（g/L）	DD（μg/L）	PLT（×10⁹/L）	Hb（g/L）
RA组	95	71.60±10.60^**	62.50±15.80^**	1.35±0.63^**	3.71±0.96^*	522.20±79.20^**	374.50±69.50^**	85.90±8.20^**
活动期组	50	90.44±11.82^##	57.15±22.91^#	0.84±0.17^##	4.35±1.69^#	965.12±29.68^##	477.23±6.37^##	67.56±9.45^##
稳定期组	45	32.87±10.71	26.52±3.40	1.77±0.46	3.02±0.45	167.45±10.22	226.10±4.99	101.68±14.65
正常对照组	90	12.50±5.90	8.40±0.78	2.64±0.88	1.99±1.01	93.80±5.70	151.30±33.90	108.60±13.50

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