Correlations between serum 25-hydroxyvitamin D and 4 blood lipid items among elderly males in Shanghai

doi:10.3969/j.issn.1673-8640.2016.09.013

Abstract

Abstract:

Objective To investigate the relationships of serum 25-hydroxyvitamin D [25（OH）D] with triglyceride （TG）,total cholesterol（TC）,high-density lipoprotein cholesterol （HDL-C） and low-density lipoprotein cholesterol （LDL-C） among elderly males in Shanghai. Methods A total of 686 elderly males participating healthy examination were enrolled. Their ages,heights and weights were recorded. Fasting venous blood samples were collected,and the 4 blood lipid levels and 25（OH）D were determined. According to the levels of 25（OH）D ,the classification was performed,G1,G2,G3 and G4 groups. The factors for blood lipid levels between G1 and G4 groups were compared. The correlations of 25（OH）D with blood lipid levels were analyzed regressively. Results Body mass index （BMI） in G1 group was lower than that in G4 group（P=0.001）,and HDL-C in G1 group was higher than that in G4 group（P<0.001）. There was no statistical significance for ages,LDL-C,TC and TG between G1 and G4 groups（P>0.05）. HDL-C was correlated positively with 25（OH）D （R²=0.161 8,P<0.001）. After the adjustment for ages and BMI,HDL-C increased by 0.01 mmol/L with serum 25（OH）D increasing by10 nmol/L. Conclusions HDL-C in elderly males may be affected by 25（OH）D.

Key words: 25-Hydroxyvitamin D, Blood lipid, Elderly

CLC Number:

R446.1

YANG Jing, SONG Binbin, WANG Beili, WU Jiong, ZHANG Chunyan, GUO Wei, PAN Baishen. Correlations between serum 25-hydroxyvitamin D and 4 blood lipid items among elderly males in Shanghai[J]. Laboratory Medicine, 2016, 31(9): 792-796.

Figures/Tables 4

References 22

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组别	例数	25（OH）D（nmol/L）	年龄（岁）	BMI （kg/m²）	HDL-C （mmol/L）	LDL-C （mmol/L）	TG （mmol/L）	TC （mmol/L）
G1组	172	86.23±15.72	73.46±9.90	23.39±3.18	1.59±0.44	2.57±0.77	1.75±0.83	4.82±0.85
G2组	171	58.40±5.49	73.46±9.90	23.85±2.95	1.45±0.38	2.70±0.81	1.73±1.02	4.88±0.93
G3组	171	42.62±3.85	71.82±11.81	24.41±3.51	1.45±0.35	2.64±0.78	1.76±1.33	4.82±0.92
G4组	172	27.58±5.95^**	72.81±12.80	24.18±3.40^*	1.44±0.41^**	2.60±0.79	1.75±1.06	4.78±0.93

组别	例数	25（OH）D（nmol/L）	年龄（岁）	BMI （kg/m²）	HDL-C （mmol/L）	LDL-C （mmol/L）	TG （mmol/L）	TC （mmol/L）
G1组	172	86.23±15.72	73.46±9.90	23.39±3.18	1.59±0.44	2.57±0.77	1.75±0.83	4.82±0.85
G2组	171	58.40±5.49	73.46±9.90	23.85±2.95	1.45±0.38	2.70±0.81	1.73±1.02	4.88±0.93
G3组	171	42.62±3.85	71.82±11.81	24.41±3.51	1.45±0.35	2.64±0.78	1.76±1.33	4.82±0.92
G4组	172	27.58±5.95^**	72.81±12.80	24.18±3.40^*	1.44±0.41^**	2.60±0.79	1.75±1.06	4.78±0.93

项目	偏回归系数	标准化偏回归系数	P值
年龄	0.007	0.187	<0.001
BMI	-0.043	-0.355	<0.001
25（OH）D	0.002	0.125	<0.001

项目	偏回归系数	标准化偏回归系数	P值
年龄	0.007	0.187	<0.001
BMI	-0.043	-0.355	<0.001
25（OH）D	0.002	0.125	<0.001

项目	模式	偏回归系数	标准化偏回归系数	P值
年龄	Model1	0.005	0.134	<0.001
BMI	Model2	-0.038	-0.310	<0.001
25（OH）D	Model3	0.001	0.076	<0.001