Laboratory Medicine ›› 2016, Vol. 31 ›› Issue (3): 159-162.DOI: 10.3969/j.issn.1673-8640.2016.03.002

• Orginal Article • Previous Articles     Next Articles

Research progress of cytomegalovirus envelope glycoprotein B,H and N and their genotypes

DONG Niuniu, XU Jin   

  1. Clinical Laboratory Center,Children's Hospital of Fudan University,Shanghai 201102,China
  • Received:2015-08-23 Online:2016-03-30 Published:2016-04-08

Abstract:

Cytomegalovirus (CMV) infections are very common in human beings. Most of the CMV infections are asymptomatic,however, symptomatic CMV infections in children can cause serious complications. CMV envelope glycoprotein is the main component of the outermost lipid bilayer membrane of CMV and plays an important role in CMV entry and spread between cells. The current situation and prospect of the relationship between gene subtypes and 3 envelope glycoproteins [glycoprotein B(gB),glycoprotein H( gH ) and glycoprotein N( gN )] are reviewed and summarized in this review,in order to provide new ideas for CMV studies.

Key words: Cytomegalovirus, Cytomegalovirus infections, Genotype

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