Laboratory Medicine ›› 2025, Vol. 40 ›› Issue (1): 96-101.DOI: 10.3969/j.issn.1673-8640.2025.01.017

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Human phospholipid scramblase 1 in antiviral infection

MA Xinxin1, LU Hongxiang2, SHI Qinghai3()   

  1. 1. Graduate School of Xinjiang Medical University,Urumqi 830000,Xinjiang,China
    2. Clinical Laboratory Diagnostic Center,General Hospital of Xinjiang Military Command,Urumqi 830000,Xinjiang,China
    3. Department of Traumatic Orthopedics,General Hospital of Xinjiang Military Command,Urumqi 830000,Xinjiang,China
  • Received:2024-05-06 Revised:2024-09-27 Online:2025-01-30 Published:2025-02-17

Abstract:

Human phospholipid scramblase 1(hPLSCR1)is a member of the transmembrane protein family that mediates the cross-layer movement of membrane phospholipids in a Ca2+ dependent manner and plays a role in cell signal transduction,maturation and apoptosis. It has the potential to become a therapeutic target or biomarker for related diseases. This review focuses on the research progress of hPLSCR1 in antiviral infection.

Key words: Human phospholipid scramblase 1, Infection, Virus

CLC Number: