Field application evaluation of intelligent oropharyngeal swab sampling robot

doi:10.3969/j.issn.1673-8640.2025.01.016

Abstract

Abstract:

Objective To evaluate the effectiveness and accuracy of intelligent oropharyngeal swab sampling robot for on-site human oropharyngeal swab sampling，and to analyze the related factors that may affect the sampling process of the intelligent oropharyngeal swab sampling robot. Methods Totally，168 teachers and students of Shanxi Medical University were enrolled to participate in on-site intelligent robot sampling. The 52 of them were sampled by both artificial and intelligent robot，and 116 were sampled only by intelligent robot. Questionnaires containing basic information and sampling comfort were collected. Real-time fluorescence quantitation polymerase chain reaction（PCR）was used for nucleic acid determinations of novel coronavirus，influenza A virus，influenza B virus，respiratory syncytial virus，adenovirus，human rhinovirus and mycoplasma pneumoniae，and the difference in determination results of subjects with different basic characteristics of the 2 sampling methods was compared. Results The internal standard cycle threshold（Ct）value of the intelligent robot sampling（29.5±1.8） was lower than that of artificial sampling（30.4±2.0）（P<0.05）. There was statistical significance in Ct values of internal standard between the 2 sampling methods of female subjects and tall subjects（P<0.05）. There was no statistical significance in the nucleic acid determination results of novel coronavirus，influenza A virus，influenza B virus，respiratory syncytial virus，adenovirus，human rhinovirus and mycoplasma pneumoniae between the 2 sampling methods （P>0.05）. The questionnaire showed that 72% of the subjects receiving intelligent robot sampling had no pharyngeal stimulation response，and there was no statistical significance in the overall composition ratio of pharyngeal stimulation response and sampling comfort of subjects with different genders and heights（P>0.05）. The gender and height of the subjects had no correlation with the pharyngeal stimulation response and sampling comfort（P>0.05）. Conclusions The intelligent oropharyngeal swab sampling robot can carry out standardized sampling for different populations. Under the premise of ensuring sample quality，the sampling process can avoid cross infection and reduce the burden of medical personnel.

Key words: Intelligent oropharyngeal swab sampling robot, Respiratory infectious disease, Oropharyngeal swab sampling, Pathogen nucleic acid determination, On-site application

CLC Number:

R446.1

QIN Shuo, WANG Ying, LIU Li, XIONG Yi, TIAN Yong, WANG Xueqing, XIONG Yanwen, LI Shaoqiang, ZHOU Chengzhi, WANG Xiaoling, LIU Zhizhen. Field application evaluation of intelligent oropharyngeal swab sampling robot[J]. Laboratory Medicine, 2025, 40(1): 90-95.

Figures/Tables 7

References 14

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组别	例数	年龄/岁	性别		身高/cm	体重/kg
组别	例数	年龄/岁	男/例	女/例	身高/cm	体重/kg
人工采样组	52	27.2±5.8	9	43	167.0±6.5	59.6±9.3
机器人采样组	168	22.9±4.8	53	115	167.0±7.4	59.9±10.4

组别	例数	年龄/岁	性别		身高/cm	体重/kg
组别	例数	年龄/岁	男/例	女/例	身高/cm	体重/kg
人工采样组	52	27.2±5.8	9	43	167.0±6.5	59.6±9.3
机器人采样组	168	22.9±4.8	53	115	167.0±7.4	59.9±10.4

项目	无咽部刺激反应	有咽部刺激反应	合计	χ²值	P值
性别				0.457	0.499
男性	40	13	53
女性	81	34	115
身高				0.380	0.537
正常身高	34	11	45
高身高	87	36	123
合计	121	47	168

项目	无咽部刺激反应	有咽部刺激反应	合计	χ²值	P值
性别				0.457	0.499
男性	40	13	53
女性	81	34	115
身高				0.380	0.537
正常身高	34	11	45
高身高	87	36	123
合计	121	47	168

项目	不适	一般	舒适	χ²值	P值
性别				0.743	0.774
男性	2	13	38
女性	8	25	82
身高				4.135	0.127
正常身高	0	12	33
高身高	10	26	87
合计	10	38	120