Laboratory Medicine ›› 2019, Vol. 34 ›› Issue (1): 47-50.DOI: 10.3969/j.issn.1673-8640.2019.01.010
Previous Articles Next Articles
Received:
2017-06-06
Online:
2019-01-30
Published:
2019-01-29
CLC Number:
Add to citation manager EndNote|Ris|BibTeX
URL: https://www.shjyyx.com/EN/10.3969/j.issn.1673-8640.2019.01.010
组别 | 例数 | 性别 | 孕龄(周) | 出生体质量(g) | Apgar评分(分) | 入组日龄(d) | 肠道症状阳性 [例(%)] | |
---|---|---|---|---|---|---|---|---|
男 | 女 | |||||||
NEC组 | 31 | 17 | 14 | 32.77±2.14 | 2 344.87±368.88 | 7.58±1.20 | 5.68±2.07 | 31(100.0) |
对照组 | 38 | 21 | 17 | 32.66±2.05 | 2 203.32±248.09 | 7.79±1.09 | 6.53±1.67 | 26(68.4) |
统计值 | 0.001 | 0.220 | 1.830 | -0.750 | -1.880 | 11.850 | ||
P值 | 0.970 | 0.830 | 0.070 | 0.450 | 0.060 | 0.001 |
组别 | 例数 | 性别 | 孕龄(周) | 出生体质量(g) | Apgar评分(分) | 入组日龄(d) | 肠道症状阳性 [例(%)] | |
---|---|---|---|---|---|---|---|---|
男 | 女 | |||||||
NEC组 | 31 | 17 | 14 | 32.77±2.14 | 2 344.87±368.88 | 7.58±1.20 | 5.68±2.07 | 31(100.0) |
对照组 | 38 | 21 | 17 | 32.66±2.05 | 2 203.32±248.09 | 7.79±1.09 | 6.53±1.67 | 26(68.4) |
统计值 | 0.001 | 0.220 | 1.830 | -0.750 | -1.880 | 11.850 | ||
P值 | 0.970 | 0.830 | 0.070 | 0.450 | 0.060 | 0.001 |
组别 | 例数 | 正常菌群 | 菌群紊乱 | 肠道菌群紊乱情况 | ||
---|---|---|---|---|---|---|
Ⅰ度失调 | Ⅱ度失调 | Ⅲ度失调 | ||||
NEC组 | 31 | 7(22.58) | 24(77.42)* | 6(19.35) | 10(32.26) | 8(25.81) |
对照组 | 38 | 21(55.26) | 17(44.73) | 7(18.42) | 4(10.53) | 6(15.79) |
组别 | 例数 | 正常菌群 | 菌群紊乱 | 肠道菌群紊乱情况 | ||
---|---|---|---|---|---|---|
Ⅰ度失调 | Ⅱ度失调 | Ⅲ度失调 | ||||
NEC组 | 31 | 7(22.58) | 24(77.42)* | 6(19.35) | 10(32.26) | 8(25.81) |
对照组 | 38 | 21(55.26) | 17(44.73) | 7(18.42) | 4(10.53) | 6(15.79) |
组别 | 例数 | 正常菌群 | 菌群紊乱 | 肠道菌群紊乱情况 | ||
---|---|---|---|---|---|---|
Ⅰ度失调 | Ⅱ度失调 | Ⅲ度失调 | ||||
NEC组 | 31 | 5(16.13) | 26(83.87)* | 6(19.35) | 11(35.48) | 9(29.03) |
对照组 | 38 | 18(47.37) | 20(52.63) | 7(18.42) | 6(15.79) | 7(18.42) |
组别 | 例数 | 正常菌群 | 菌群紊乱 | 肠道菌群紊乱情况 | ||
---|---|---|---|---|---|---|
Ⅰ度失调 | Ⅱ度失调 | Ⅲ度失调 | ||||
NEC组 | 31 | 5(16.13) | 26(83.87)* | 6(19.35) | 11(35.48) | 9(29.03) |
对照组 | 38 | 18(47.37) | 20(52.63) | 7(18.42) | 6(15.79) | 7(18.42) |
组别 | 例数 | HBD1 | HBD2 | ||||
---|---|---|---|---|---|---|---|
入院首日 | 确诊后2 d | 出科当日 | 入院首日 | 确诊后2 d | 出科当日 | ||
NEC组 | 31 | 149.89±26.48 | 107.95±13.90 | 145.71±16.16 | 387.26±33.55 | 373.55±35.58 | 388.63±45.97 |
对照组 | 38 | 136.68±25.48 | 95.13±22.09 | 134.61±18.52 | 361.68±25.48 | 341.84±25.98 | 355.84±21.46 |
t值 | 2.097 | 2.809 | 2.658 | 3.598 | 4.273 | 3.906 | |
P值 | 0.040 | 0.007 | 0.010 | 0.001 | <0.001 | <0.001 |
组别 | 例数 | HBD1 | HBD2 | ||||
---|---|---|---|---|---|---|---|
入院首日 | 确诊后2 d | 出科当日 | 入院首日 | 确诊后2 d | 出科当日 | ||
NEC组 | 31 | 149.89±26.48 | 107.95±13.90 | 145.71±16.16 | 387.26±33.55 | 373.55±35.58 | 388.63±45.97 |
对照组 | 38 | 136.68±25.48 | 95.13±22.09 | 134.61±18.52 | 361.68±25.48 | 341.84±25.98 | 355.84±21.46 |
t值 | 2.097 | 2.809 | 2.658 | 3.598 | 4.273 | 3.906 | |
P值 | 0.040 | 0.007 | 0.010 | 0.001 | <0.001 | <0.001 |
组别 | 例数 | HBD1 | HBD2 | ||||
---|---|---|---|---|---|---|---|
入院首日 | 确诊后2 d | 出科当日 | 入院首日 | 确诊后2 d | 出科当日 | ||
轻症组NEC | 22 | 143.95±20.13 | 100.68±23.51 | 139.00±18.82 | 368.95±22.56 | 349.09±26.07 | 360.09±22.49 |
重症组NEC | 9 | 118.89±21.62 | 76.89±13.00 | 123.89±13.20 | 343.89±24.43 | 324.11±15.79 | 342.11±18.60 |
t值 | 2.744 | 3.591 | 2.189 | 2.650 | 3.263 | 2.114 | |
P值 | 0.010 | 0.001 | 0.037 | 0.010 | 0.012 | 0.043 |
组别 | 例数 | HBD1 | HBD2 | ||||
---|---|---|---|---|---|---|---|
入院首日 | 确诊后2 d | 出科当日 | 入院首日 | 确诊后2 d | 出科当日 | ||
轻症组NEC | 22 | 143.95±20.13 | 100.68±23.51 | 139.00±18.82 | 368.95±22.56 | 349.09±26.07 | 360.09±22.49 |
重症组NEC | 9 | 118.89±21.62 | 76.89±13.00 | 123.89±13.20 | 343.89±24.43 | 324.11±15.79 | 342.11±18.60 |
t值 | 2.744 | 3.591 | 2.189 | 2.650 | 3.263 | 2.114 | |
P值 | 0.010 | 0.001 | 0.037 | 0.010 | 0.012 | 0.043 |
[1] | 曾振华. 新生儿坏死性小肠结肠炎研究现状及发展趋势探究[J]. 中外医学研究,2014,12(27): 152-153. |
[2] | 孙红, 薛越, 黄宁. 抗菌肽抗菌机制的研究进展[J]. 中国抗生素杂志, 2013,38(8): 568-572. |
[3] | 吴琼,陈洪友,屠丽红,等. 人β-防御素在空肠弯曲菌感染中的表达与调控[J]. 检验医学, 2016,31(8): 662-666. |
[4] | 胡庆丰, 陈同辛. 防御素研究进展[J]. 临床儿科杂志, 2015,33(9): 831-834. |
[5] | 杨玉荣,刘占举,梁宏德. 防御素在炎症性肠病中的作用机制[J]. 世界华人消化杂志, 2010,18(29): 3101-3106. |
[6] | 胡亚美,江载芳. 诸福棠实用儿科学[M]. 7版.北京:人民卫生出版社,2011:475-476. |
[7] | 张秀荣,周峻元. 肠道菌群粪便涂片检查图谱[M]. 北京:人民军医出版社,2000:63-65. |
[8] | 晏俪鸶. 新生儿坏死性小肠结肠炎发病原因及预后研究进展[J]. 国际儿科学杂志, 2016, 43(6): 470-473. |
[9] | 王红, 宋朝敏, 吴斌,等. 新生儿坏死性小肠结肠炎的防治进展[J]. 国外医学(儿科学分册), 2005, 32(6): 340-342. |
[10] | ZILBAUER M, JENKE A, WENZEL G, et al.Expression of human beta-defensins in children with chronic inflammatory bowel disease[J]. PLoS One, 2010,5(10): e15389. |
[11] | 夏婧, 吴捷,魏克伦. 无乳糖奶粉辅助治疗婴儿急性腹泻病的疗效研究[J]. 国际儿科学杂志, 2015,42(5): 592-594. |
[12] | MORGAN X C, HUTTENHOWER C. Meta'omic analytic techniques for studying the intestinal microbiome[J]. Gastroenterology, 2014,146(6): 1437-1448. el. |
[1] | FAN Lieying. Research status and application prospects of biomarkers for membranous nephropathy [J]. Laboratory Medicine, 2023, 38(12): 1111-1114. |
[2] | SUN Lincheng, LI Jianfeng, CHENG Weili, JI Panyun. Roles of anti-PLA2R IgG4 antibody and PLA2R IgG4/IgG ratio in primary membranous nephropathy [J]. Laboratory Medicine, 2023, 38(12): 1115-1120. |
[3] | LIU Qingyang, YUAN Jianming, XIA Jinjun, JIANG Fengying, WANG Qiubo, WANG Xiaoming. CXCL9 as a potential diagnostic marker of rheumatoid arthritis based on GEO database and experimental verification [J]. Laboratory Medicine, 2023, 38(12): 1121-1129. |
[4] | YANG Xiao, LI Enling, WU Lixia, DAI Yingxin, WANG Zhiqing, HUANG Hao, ZHENG Bing. Influence of cytoplasmic antinuclear antibody on indirect immunofluorescence assay based antineutrophil cytoplasmic antibody determination [J]. Laboratory Medicine, 2023, 38(12): 1135-1140. |
[5] | XIANG Jin, LIU Aiping, HU Yao, WU Zhiyuan, CAO Guojun, GUAN Ming. ANA profiles in COVID-19 patients and influence of serum heat-inactivation on ANA determination [J]. Laboratory Medicine, 2023, 38(12): 1141-1146. |
[6] | CHENG Yu, XU Zhen, LU Liu, DING Menglei, YU Shanshan, ZONG Ming, FAN Lieying. Expression and risk factors of anti-ACE-2 antibody in serum of patients with COVID-19 [J]. Laboratory Medicine, 2023, 38(12): 1147-1152. |
[7] | . [J]. Laboratory Medicine, 2023, 38(12): 1153-1156. |
[8] | . [J]. Laboratory Medicine, 2023, 38(12): 1157-1159. |
[9] | WANG Hongling, LIU Mengna, BAI Ping, LIAO Huanjin. Risk factors of relapse following allogeneic hematopoietic stem cell transplantation in patients with acute myeloid leukemia [J]. Laboratory Medicine, 2023, 38(12): 1160-1166. |
[10] | YANG Xilan, WANG Jinyu, LIU Shuyu, ZHAN Yiyang, LIU Jing, JIA Jian. Correlation between hyperlipidemia and endothelial microparticles in elderly patients from Gulou Community in Nanjing [J]. Laboratory Medicine, 2023, 38(12): 1167-1172. |
[11] | DAI Fangfang, LU Xinxin, YU Yanhua, CHEN Ming, SUN Guizhen. Analysis of Mycobacterium infection in HIV/AIDS patients [J]. Laboratory Medicine, 2023, 38(12): 1173-1176. |
[12] | GU Yu, LIANG Xiaoyan, MA Shenghui, TONG Na, CHENG Mingyan, YAN Zejun. Expression and near-term prognostic predictive value of plasma biomarkers in chronic kidney disease patients with thromboembolism [J]. Laboratory Medicine, 2023, 38(12): 1177-1182. |
[13] | . [J]. Laboratory Medicine, 2023, 38(12): 1183-1185. |
[14] | . [J]. Laboratory Medicine, 2023, 38(12): 1186-1190. |
[15] | . [J]. Laboratory Medicine, 2023, 38(12): 1191-1194. |
Viewed | ||||||
Full text |
|
|||||
Abstract |
|
|||||