Research on the relationship between the level changes of RDW-CV and left ventricular mass index in patients with essential hypertension

doi:10.3969/j.issn.1673-8640.2015.10.008

Abstract

Abstract: Objective

To investigate the relationship between the level changes of red blood cell distribution width coefficient of variation (RDW-CV) and left ventricular mass index (LVMI) in patients with essential hypertension (EH).

Methods

A total of 100 patients with EH were enrolled as EH group, and 30 healthy subjects were enrolled as healthy control group. Echocardiography was used to measure related indices, and LVMI was calculated. According to the diagnostic criteria of left ventricular hypertrophy (LVH)(LVMI for male>125 g/m² and LVMI for female>110 g/m²), EH group was classified into 2 groups, EH with LVH group (LVH group, 40 cases) and EH without LVH group (NLVH group, 60 cases). RDW-CV, mean corpuscular volume (MCV), hemoglobin (Hb), high-sensitivity C reaction protein (hs-CRP) and left ventricular ejection fraction (LVEF) were determined, and a correlation analysis on RDW-CV level changes and LVMI was performed.

Results

MCV, Hb and LVEF among the 3 groups had no statistical significance (P>0.05). The level of RDW-CV and LVMI in NLVH group and LVH group were significantly higher than those in healthy control group (P<0.01). The level of RDW-CV and LVMI elevated significantly in LVH group than in NLVH group (P<0.01). Pearson linear correlation analysis showed that RDW-CV was positively correlated with LVMI in EH patients(r=0.36, P<0.05).

Conclusions

The expression level of RDW-CV elevates in patients with EH, which is relative to LVMI.

Key words: Red blood cell distribution width coefficient of variation, Essential hypertension, Left ventricular mass index, Left ventricular hypertrophy

CLC Number:

R446.1

LIU Jing, LI Bin, LIU Shuli, ZHENG Xi. Research on the relationship between the level changes of RDW-CV and left ventricular mass index in patients with essential hypertension[J]. Laboratory Medicine, 2015, 30(10): 998-1001.

Figures/Tables 3

References 12

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组别	例数	RDW-CV(%)	MCV(fL)	Hb(g/L)	hs-CRP(mg/L)	LVEF(%)	LVMI(g/m²)
正常对照组	30	12.66±0.85	86.88±6.82	132.22±11.02	1.66±0.90	56.35±4.76	72.26±7.43
NLVH组	60	14.98±0.93^*	87.75±5.78	130.29±10.53	2.74±0.68^*	55.34±5.01	92.24±8.54^*
LVH组	40	16.95±1.85^*#	85.88±5.84	131.62±12.76	3.91±0.77^*#	55.03±5.23	132.38±9.22^*#

组别	例数	RDW-CV(%)	MCV(fL)	Hb(g/L)	hs-CRP(mg/L)	LVEF(%)	LVMI(g/m²)
正常对照组	30	12.66±0.85	86.88±6.82	132.22±11.02	1.66±0.90	56.35±4.76	72.26±7.43
NLVH组	60	14.98±0.93^*	87.75±5.78	130.29±10.53	2.74±0.68^*	55.34±5.01	92.24±8.54^*
LVH组	40	16.95±1.85^*#	85.88±5.84	131.62±12.76	3.91±0.77^*#	55.03±5.23	132.38±9.22^*#