The application of Mycobacterium tuberculosis direct test in the diagnosis of AIDS co-infection with tuberculosis

Abstract

Abstract: Objective　To investigate the clinical application of Mycobacterium tuberculosis direct（MTD） test in the diagnosis of acquired immune deficiency syndrome（AIDS） co-infection with tuberculosis. Methods　The sputum samples of 127 AIDS patients suspected of tuberculosis co-infection were determined by MTD test， Mycobacterium tuberculosis culturing and acid-fast stain test. Sputum samples of 25 inpatients suspected of tuberculosis without human immunodeficiency virus（HIV） infection were analyzed as controls. Results　The sputum positive rates of the 127 AIDS patients were 29.1%， 25.2% and 18.9% by MTD test，Mycobacterium tuberculosis culturing and acid-fast stain test， respectively. The positive rates of the controls were 44.0%， 44.0% and 40.0% by MTD test， Mycobacterium tuberculosis culturing and acid-fast stain test，respectively. Conclusions　MTD test has application value in AIDS patients suspected of tuberculosis co-infection. It can improve the positive rate and provide the laboratory results within 1 d.

Key words: Mycobacterium tuberculosis direct, Acquired immune deficiency syndrome, Tuberculosis

YANG Shao-Min;FAN Yi-Shan;LI Hui-Qin;GAO Li;YANG Bi-Hui;ZHANG Mi;LI Zheng-Lun;ZHOU Zeng-Quan. The application of Mycobacterium tuberculosis direct test in the diagnosis of AIDS co-infection with tuberculosis[J]. , 2012, 27(6): 457-460.

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