Abstract:

Multiple myeloma(MM) is a plasma cell monoclonal malignant proliferative disease. The myeloma cells infiltrate bone and soft tissue, produce M protein and cause bone destruction, anemia, renal insufficiency, repeated infection and so on. Through the statistics, the incidence of MM in all malignant tumors accounts for about 1%, and its incidence in blood system of malignant tumor is more than 10%.The pathogenesis of MM is not fully clear, the complex and various clinical symptoms lead to misdiagnosis or missed diagnosis easily. The difference of laboratory examination may lead to difficult disease diagnosis and differential diagnosis. Therefore, investigating the clinical and laboratory diagnosis characteristics of MM has clinical significance for the early detection, early diagnosis and early treatment of MM. In this paper, the clinical and laboratory diagnosis characteristics of MM are reviewed in detail.

Key words: Multiple myeloma, Laboratory examination, Diagnosis