Laboratory Medicine ›› 2015, Vol. 30 ›› Issue (7): 680-683.DOI: 10.3969/j.issn.1673-8640.2015.07.004

• Orginal Article • Previous Articles     Next Articles

Applicability of glomerular filtration rate equations in different populations

BIAN Bingxian, ZHOU Yunlan, SHEN Lisong   

  1. Department of Clinical Laboratory, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, China
  • Received:2015-02-23 Online:2015-07-30 Published:2015-08-28

Abstract:

Today, estimated glomerular filtration rate (eGFR) equations based on general population are widely used, however, some equations fail to provide the same performance in certain population because of different features. This review aims to discuss the development and comparative performance of eGFR equations in different populations, including Chinese, children, patients with diabetes mellitus, patients with heart failure and elderly. We suggest that it should pay attention to the standardization of creatinine and cystatin C (Cys C) determinations and the differentiation and localization of eGFR equations in clinical study and application.

Key words: Glomerular filtration rate, Estimated glomerular filtration rate equation, Creatinine, Cystatin C

CLC Number: