The application of mass spectrometry in clinical biochemistry

doi:10.3969/j.issn.1673-8640.2015.05.001

Abstract

Abstract:

Recently, mass spectrometry has been playing more and more important roles in clinical laboratory medicine. The development of gas or high-performance liquid chromatography and tandem mass spectrometry technologies has expanded the application of mass spectrometry, and it becomes an efficient tool for clinical biochemical determination. This article introduces the technical principle of mass spectrometry and presents the utilization in clinical biochemistry, such as newborn screening for genetic diseases and so on. Mass spectrometry has shown great potential with the advantages of high specificity, high sensitivity and low limit of determination in clinical biochemistry.

Key words: Mass spectrometry, Clinical biochemistry determination

CLC Number:

R446.1

ZHANG Ziqiang, LI Yan. The application of mass spectrometry in clinical biochemistry[J]. Laboratory Medicine, 2015, 30(5): 407-409.

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