Comparison on the detection significance of blood glucose and glycated serum protein among traumatic fracture patients

doi:10.3969/j.issn.1673-8640.2015.02.012

Abstract

Abstract: Objective

To study the fact of blood glucose (Glu) rising being the result of diabetes mellitus or post-traumatic stress response of body through detecting the changes of Glu and glycated serum protein (GSP).

Methods

The 87 patients with acute traumatic fracture were classified into 3 groups according to the presence or absence of type 2 diabetes mellitus, traumatic fracture with diabetes group(17 cases), traumatic fracture with unknown diabetes group (22 cases diagnosed as diabetes after hospitalization) and traumatic fracture without diabetes group (48 cases). The Glu and GSP levels of each group were measured by glucose oxidase method and fructosamine assay when hospitalized and cured. A total of 30 healthy subjects were enrolled as healthy controls.

Results

The Glu levels of acute traumatic fracture groups were significantly higher than that of control group (P<0.05), especially traumatic fracture with unknown diabetes group, and there was statistical significance (P<0.05). The level of GSP of traumatic fracture with unknown diabetes group was higher than those of the other 3 groups (P<0.05), while the GSP levels of the other 3 groups had no statistical significance (P>0.05). The Glu level of acute traumatic fracture groups returned to normal level when cured, while the GSP level of traumatic fracture with unknown diabetes group increased and was significantly higher than those of the other 3 groups (P<0.05), due to high level of Glu. The Glu level of traumatic fracture without diabetes group when cured was significantly lower than that when hospitalized (P<0.05), while there was no significant difference for GSP level (P>0.05).

Conclusions

The detection of Glu could be used as a method of monitoring and evaluating the prognosis of acute traumatic fracture. GSP level could be the important reference of distinguishing Glu rising because of diabetes mellitus or post-traumatic stress response of body.

Key words: Blood glucose, Glycated serum protein, Trauma, Fracture, Acute, Type 2 diabetes mellitus

CLC Number:

R446.1

LI Xiaonan, LIU Junquan. Comparison on the detection significance of blood glucose and glycated serum protein among traumatic fracture patients[J]. Laboratory Medicine, 2015, 30(2): 152-155.

Figures/Tables 1

References 13

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组别	例数	入院时		治愈出院时
组别	例数	Glu	GSP	Glu	GSP
创伤性骨折组	87
已知糖尿病组	17	8.62±0.78^*	2.20±0.35^#	5.29±0.51^△	2.33±0.25^#
未知糖尿病组	22	11.24±0.76^*	3.35±0.45	6.03±0.55^△	3.34±0.36
无糖尿病组	48	8.22±0.83^*	2.16±0.25^#	5.25±0.43^△	2.24±0.26^#
正常对照组	30	5.13±0.85	2.15±0.32^#	5.13±0.54	2.15±0.32^#

组别	例数	入院时		治愈出院时
组别	例数	Glu	GSP	Glu	GSP
创伤性骨折组	87
已知糖尿病组	17	8.62±0.78^*	2.20±0.35^#	5.29±0.51^△	2.33±0.25^#
未知糖尿病组	22	11.24±0.76^*	3.35±0.45	6.03±0.55^△	3.34±0.36
无糖尿病组	48	8.22±0.83^*	2.16±0.25^#	5.25±0.43^△	2.24±0.26^#
正常对照组	30	5.13±0.85	2.15±0.32^#	5.13±0.54	2.15±0.32^#

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