Abstract: Coagulation function determinations are usually used to analyze the causes of bleeding disorders, evaluate pre operation coagulation status and support the therapies of oral coagulation drugs. China National Accreditation Service for Conformity Assessment, College of American Pathologists and Clinical and Laboratory Standards Institute published the terms and documents of quality assurance in coagulation function determinations. Considering the account of coagulation specimens, clinical laboratories may ignore some quality requirements, affect clinical diagnosis and treatment, and influence on patients' safety of life. The review mainly focuses on the common problems and their solutions of clinical coagulation function determinations.

Key words: Coagulation function, Quality improvement, Experience exchange