Abstract:

Objective　To establish the biological reference intervals about the main parameters of blood cells among pregnant women in our laboratory. Methods　A total of 331 pregnant women who had normal and term delivery were enrolled. According to their medical records, their 2 reports of pregnancy routine blood cell tests were obtained. The results were analyzed statistically, and the biological reference intervals were calculated by SAS 8.1 software. Results　There was statistical significance in all parameters of pregnancy routine blood cell tests between the first and third trimesters (P<0.05). The results of biological reference intervals showed that the 2 sets of data about platelet (PLT), monocyte percentage (M %) and basophilic granulocyte percentage (B %) were all within current biological reference intervals, then the current biological reference intervals could be used for pregnancy. The 2 sets of data about hematocrit (HCT) and eosinophile granulocyte percentage (E %) could be combined to new biological reference intervals. The biological reference intervals for red blood cell count (RBC), hemoglobin (Hb), white blood cell count (WBC), neutrophile granulocyte percentage (N %) and lymphocyte percentage (L %) should be established according to different trimesters. Conclusions　The newly established biological reference intervals are appropriate to reflect the physiological changes during pregnancy, and can guide the clinical diagnosis and treatment effectively.

Key words: Pregnant woman, Blood cell, Biological reference interval