›› 2014, Vol. 29 ›› Issue (1): 86-90.DOI: 10.3969/j.issn.1673-8640.2014.01.021

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Common influence factors for the stability of urine storage

LUO Yi, WANG Congrong.   

  1. Shanghai Diabetes Institute, Department of Endocrinology and Metabolism, Shanghai Jiaotong University Affiliated Sixth People′s Hospital, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Clinical Center for Diabetes, Metabolic Diseases Biobank, Shanghai 200233, China
  • Received:2013-06-25 Online:2014-01-20 Published:2014-01-20

Abstract: Urine is easily accessible, can be collected noninvasively, and provides information on numerous physiological processes. Urine is a source of numerous potential biomarkers, including metabolites, cells, proteins and nucleic acids. Many factors can affect the quality of the stored urine, including the time and temperature of storage, PH and multiple freezing and thawing. However, it remains being a controversial topic on the influence of exterior factors on the stability of urine storage. With the development of proteomics and metabolomics, mounting number of metabolomic and proteomic studies attempt to identify the influence of storage conditions on urine analysis. This review presents an overview of the influence of storage conditions on urine analysis.

Key words: Urine, Storage, Stability

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