Abstract:

Objective To investigate the effect of vulva cleaning operation to the determination results of urinary biochemical indexes. Methods A total of 35 volunteers were enrolled. The morning urine samples collected when the volunteers did not clean the vulva were used as uncleaning group,and the morning urine samples collected after cleaning the vulva with 0.9% NaCl solution on the 2nd and 3rd days were used as cleaning group. Urinary microalbumin（mAlb）,chloridion（Cl^-）,creatinine（Cr）,kalium ion（K⁺）,sodion（Na⁺）,total protein（TP）,alpha₁-microglobulin（α₁-MG）,beta₂-microglobulin（β₂-MG）,IgG,transferrin（TF）,calcium（Ca）,phosphorus（P） and glucose（Glu） levels were determined,and colony count determination and bacterial species identification were performed. Results There was statistical significance in total urinary colony count between males and females in uncleaning group（P<0.05）,but urinary mAlb,Cr,IgG,Glu,Ca,P,α₁-MG and TF had no statistical significance（P>0.05）. Between males and females in cleaning group,the total urinary colony count,α₁-MG,IgG,TF,Cl^- and Na⁺ had statistical significance（P<0.05）,and there was no statistical significance in urinary mAlb,Cr,Glu,Ca and P（P>0.05）. There was statistical significance in urinary IgG in males between cleaning group and uncleaning group（P<0.05）,but there was no statistical significance in total urinary colony count,mAlb,Cr,IgG,Glu,Ca,P,α₁-MG and TF（P>0.05）. There was no statistical significance for the urinary biochemical indexes between cleaning group and uncleaning group in females（P>0.05）. Conclusions The vulva cleaning operation has an impact on the determination results of male urinary biochemical indexes,but there is no impact on the determination results of female. Therefore,the female vulva cleaning operation needs to be further optimized.

Key words: Biochemical index, Urine, Vulva cleaning, Male, Female