Abstract: Objective　To evaluate the clinical application significance of Sysmex UF-1000i urine formed element analyzer (UF-1000i analyzer) for screening funguria.   Methods　The precision，linear range and carryover rate of Candida albicans were detected by UF-1000i analyzer. A total of 200 urine samples which UF-1000i analyzer showed like yeast cell（YLC） positive and 400 YLC negative urine samples were detected by manual microscopy. Results　For UF-1000i analyzer detecting Candida albicans，the precision was 3.83%- 4.71%，the linear range was 10.0-5 873.1 cells/μL，the correlation coefficient was 0.999, and the carryover rate was 0.12%. Manual microscopy was as the gold standard，and the result of receiver operating characteristic (ROC) curve showed the best cut-off value for UF-1000i analyzer detecting YLC was 18.05 cells/μL. The sensitivity，specificity，accuracy，positive predictive value and negative predictive value of UF-1000i analyzer in the diagnosis of funguria were 97.0%，85.6%，87.5%，57.4% and 99.3%，respectively. Conclusions　UF-1000i analyzer can provide quantitative results of fungal spores. It aids to diagnose urinary tract fungal infection.

Key words: Funguria, Sysmex UF-1000i urine formed element analyzer, Microscopy