钙敏感受体及其相关信号转导通路对细胞因子分泌的调控

doi:10.3969/j.issn.1673-8640.2014.05.030

摘要/Abstract

摘要： 本文对钙敏感受体(CaSR)的结构特点、信号转导、生理作用进行了概述。重点阐述了CaSR介导的相关信号转导通路对细胞因子分泌的调控机制, 并对二者关系的研究前景进行了展望。

关键词: 钙敏感受体, 细胞因子, 核转录因子通路, 丝裂原活化蛋白激酶通路

Abstract: In this article, we summary the calcium sensing receptor(CaSR) structure, signal transduction and physiological function. The regulation mechanism of CaSR on the secretion of cytokines was described through the related signal transduction pathways, and we prospect the relations between them.

Key words: Calcium sensing receptor, Cytokine, Nuclear transcription factor-kappa B pathway, Mitogen activated protein kinase pathway

中图分类号:

R446.62

吴秋月, 孙轶华. 钙敏感受体及其相关信号转导通路对细胞因子分泌的调控[J]. 检验医学, 2014, 29(5): 564-569.

WU Qiuyue, SUN Yihua.. Calcium sensing receptor and regulation of related signal transduction pathways on the secretion of cytokine[J]. , 2014, 29(5): 564-569.

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