检验医学 ›› 2018, Vol. 33 ›› Issue (12): 1144-1147.DOI: 10.3969/j.issn.1673-8640.2018.12.020

• 综述与讲座 • 上一篇    下一篇

糖尿病患者血小板高活性状态研究进展

范志佳1, 徐黎明1, 王力1, 武强2, 王志成1()   

  1. 1. 复旦大学附属华山医院检验科,上海 200040
    2. 复旦大学附属第五人民医院检验科,上海 200240
  • 收稿日期:2017-12-10 出版日期:2018-12-26 发布日期:2018-12-27
  • 作者简介:null

    作者简介:范志佳,女,1995年生,硕士,主要从事血栓与止血研究。

  • 基金资助:
    国家自然科学基金项目(81673080)

Research progress in the platelet hyperactivity of diabetes mellitus patients

FAN Zhijia1, XU Liming1, WANG Li1, WU Qiang2, WANG Zhicheng1()   

  1. 1. Department of Clinical Laboratory,Huashan Hospital,Fudan University,Shanghai 200040,China
    2. Department of Clinical Laboratory,the Fifth People's Hospital of Fudan University,Shanghai 200240,China
  • Received:2017-12-10 Online:2018-12-26 Published:2018-12-27

摘要:

糖尿病与肿瘤、心血管疾病被并称为世界三大非传染性疾病,是由遗传和环境因素共同作用而引起的一类以代谢紊乱为特征的临床综合症。其血管并发症包括微血管病变和大血管病变,是目前导致糖尿病患者致残、致死的主要原因。在导致糖尿病血栓前状态的因素中,血小板高活性发挥了重要作用。文章对糖尿病导致血小板高活性的机制进行综述。

关键词: 糖尿病, 血管并发症, 血小板

Abstract:

Diabetes mellitus tumor and cardiovascular disease arecommon non-communicable diseases in the world Diabetes mellitus is a clinical syndrome characterized by metabolic disorders and is caused by the combination of genetic and environmental factors. Vascular complications,including microangiopathy and macroangiopathy,are major causes for its morbidity and mortality. Among the factors contributing to prothrombotic condition,platelet hyperactivity plays a role. The mechanism of platelet hyperactivity in diabetes mellitus is reviewed.

Key words: Diabetes mellitus, Vascular complication, Platelet

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