检验医学 ›› 2016, Vol. 31 ›› Issue (7): 599-602.DOI: 10.3969/j.issn.1673-8640.2016.07.013

• 技术研究与评价·论著 • 上一篇    下一篇

GeneXpert MTB/RIF系统对肺结核的诊断价值

张青, 薛冰茹, 李克诚   

  1. 瑞安市人民医院检验科,浙江 瑞安 325200
  • 收稿日期:2015-09-23 出版日期:2016-07-30 发布日期:2016-08-10
  • 作者简介:null

    作者简介:张青,男,1987年生,学士,技师,主要从事临床微生物学和细菌的耐药机制研究。

GeneXpert MTB/RIF system in the diagnosis of pulmonary tuberculosis

ZHANG Qing, XU Bingru, LI Kecheng   

  1. Department of Clinical Laboratory,Ruian People's Hospital,Ruian 325200,Zhejiang,China
  • Received:2015-09-23 Online:2016-07-30 Published:2016-08-10

摘要: 目的

评价GeneXpert MTB/RIF系统对肺结核的诊断价值。

方法

对拟诊为肺结核的99例患者痰样本分别进行痰涂片抗酸染色镜检、结核分枝杆菌(MTB)培养和GeneXpert MTB/RIF系统分子检测,对比分析结果。

结果

在所有拟诊病例中,GeneXpert MTB/RIF系统、MTB培养和抗酸染色镜检的阳性率分别为29.6%、25.7%、20.2%;在确诊病例中,GeneXpert MTB/RIF系统、MTB培养和抗酸染色镜检的阳性率分别为100.0%、100.0%、80.0%。

结论

GeneXpert MTB/RIF系统对肺结核的诊断和疗效评估具有重要价值。

关键词: GeneXpert MTB/RIF系统, 抗酸染色, 结核分枝杆菌培养, 肺结核

Abstract:

Objective To evaluate the significance of GeneXpert MTB/RIF system in the diagnosis of pulmonary tuberculosis. Methods A total of 99 sputum samples from suspected pulmonary tuberculosis patients were collected,and the samples were determined by acid fast staining,Mycobacterium tuberculosis(MTB) culture and GeneXpert MTB/RIF system. Results The positive rates of GeneXpert MTB/RIF system,MTB culture and acid fast staining were 29.6%,25.7% and 20.2% in all suspected pulmonary tuberculosis patients. The positive rates of GeneXpert MTB/RIF system,MTB culture and acid fast staining were 100.0%,100.0% and 80.0% in confirmed cases. Conclusions GeneXpert MTB/RIF system is of significance in the diagnosis and treatment efficiency evaluation of pulmonary tuberculosis.

Key words: GeneXpert MTB/RIF system, Acid fast staining, Mycobacterium tuberculosis culture, Pulmonary tuberculosis

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