Patient medians and exponentially weighted moving average in comparing peripheral blood RBC count results of different instruments

doi:10.3969/j.issn.1673-8640.2022.011.019

Abstract

Abstract:

Objective To compare the application of patient medians and exponentially weighted moving average（EWMA） in in-laboratory comparison of peripheral blood red blood cell（RBC） count results by different instruments. Methods From July 1st 2020 to December 31st 2020，based on AI-MA patient datum quality control intelligent monitoring platform，EWMA method and median method were used to compare and analyze the monthly and daily deviations of 3 cut-off concentrations obtained between 3 comparison instruments（A2，A3 and A4） and reference instrument（A1）. Results When month was taken as statistical cycle，the monthly deviation obtained by EWMA method was within the allowable range，and the monthly deviation obtained by median method was inconsistent with the L1 concentration of one instrument. When taking day as statistical cycle，the daily deviation of L2 concentration obtained by the 2 methods was within the allowable range，and there were many nonconformities in the daily deviation of L1 and L3 concentrations. Conclusions The monitoring efficiency of EWMA method and median method for continuous real-time comparison of peripheral blood results between instruments in the laboratory is basically the same. It is an economic and practical comparison method.

Key words: Peripheral blood, In-laboratory, Between-instrument comparison, Median method, Exponentially weighted moving average method

CLC Number:

R446.1

WANG Huiru, WANG Shenghua, HUANG Shanshan, WU Hao, YU Wenjing, GUO Yinghui. Patient medians and exponentially weighted moving average in comparing peripheral blood RBC count results of different instruments[J]. Laboratory Medicine, 2022, 37(11): 1093-1097.

Figures/Tables 9

References 9

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仪器	质控浓度/ （×10¹²/L）	加权系数	EWMA累积均值	EWMA累积变异系数/%	个数/个	在控数/个
XN1000血液分析仪	3.0~3.9	0.05	3.54	1.33	2 174	2 174
	4.0~5.0	0.05	4.52	1.08	17 879	17 879
	5.1~6.1	0.05	5.30	0.60	1 602	1 602
XS500iC血液分析仪	3.0~3.9	0.05	3.56	1.03	864	864
	4.0~5.0	0.05	4.57	1.33	16 564	16 564
	5.1~6.1	0.05	5.30	0.64	1 999	1 999

仪器	质控浓度/ （×10¹²/L）	加权系数	EWMA累积均值	EWMA累积变异系数/%	个数/个	在控数/个
XN1000血液分析仪	3.0~3.9	0.05	3.54	1.33	2 174	2 174
	4.0~5.0	0.05	4.52	1.08	17 879	17 879
	5.1~6.1	0.05	5.30	0.60	1 602	1 602
XS500iC血液分析仪	3.0~3.9	0.05	3.56	1.03	864	864
	4.0~5.0	0.05	4.57	1.33	16 564	16 564
	5.1~6.1	0.05	5.30	0.64	1 999	1 999

仪器	EWMA法			中位数法
仪器	L1	L2	L3	L1	L2	L3
XN-1000血液分析仪	3.54	4.52	5.30	3.61	4.53	5.24
XS-500iC血液分析仪	3.57	4.50	5.30	3.63	4.50	5.23

仪器	EWMA法			中位数法
仪器	L1	L2	L3	L1	L2	L3
XN-1000血液分析仪	3.54	4.52	5.30	3.61	4.53	5.24
XS-500iC血液分析仪	3.57	4.50	5.30	3.63	4.50	5.23

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