Abstract:

Objective To analyze the relationship between the level of Helicobacter pylori（Hp） colonization in the stomach and the metabolic syndrome（MS） based on female and male grouping，and to provide an epidemiological basis for clinically reducing the prevalence of MS. Methods The clinical data of 30 376 subjects in Huadong Hospital of Fudan University from October 2019 to September 2020 were collected and analyzed retrospectively，and the subjects were classified into MS group（3 300 cases） and non-MS group（27 076 cases）. The risk factors of MS were analyzed，and the correlation of the level of Hp colonization in the stomach with MS was evaluated. Results The prevalence of Hp was 24.1%，26.3% for males and 21.6% for females，and there was statistical significance between females and males（P<0.001）. The prevalence of MS was 10.9%，15.6% for males and 5.7% for females，and there was statistical significance between females and males（P<0.001）. In the different groups of MS scores，the prevalence of Hp in males was higher than that in females（P<0.05）. In the different groups of colonization values，the prevalence of MS in males was higher than that in females（P<0.05）. High colonization level of Hp was risk factor of MS in males. Conclusions In Shanghai physical examination population，there is a correlation between high colonization level of Hp and MS in males. It is recommended that males with Hp-positive and MS should receive Hp eradication treatment in time.

Key words: Helicobacter pylori, Colonization, Metabolic syndrome, Sex, Correlation