Laboratory Medicine ›› 2021, Vol. 36 ›› Issue (5): 565-568.DOI: 10.3969/j.issn.1673-8640.2021.05.021

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Research progress of intestinal microbiota and IL-6/gp130 signaling pathway in acute pancreatitis pathogenesis

XIAO Yingyan, CUI Yan, LI Yan   

  1. Laboratory Medicine Center,Renmin Hospital of Wuhan University,Wuhan 430060,Hubei,China
  • Received:2020-01-14 Online:2021-05-30 Published:2021-05-30

Abstract:

Acute pancreatitis is one of the most common acute abdominal diseases. It is characterized by local inflammation of the pancreas with or without changes in the function of other organs. Dysbacteriosis and activation of inflammatory response are risk factors for acute pancreatitis. This review focuses on recent advances in the study of intestinal microbiota and interleukin-6(IL-6)/glycoprotein 130(gp130) inflammatory signaling pathway in the pathogenesis of acute pancreatitis.

Key words: Intestinal microbiota, Inflammation, Interleukin-6, Glycoprotein 130, Acute pancreatitis

CLC Number: