Abstract:

Objective To investigate high-risk human papilloma virus（HPV） in screening of cervical diseases. Methods By polymerase chain reaction（PCR）,23 kinds of HPV subtypes were determined,and pathological analysis was performed by thinprep cytologic test（TCT）. Subjects were classified into 6 groups according to ages. The determination rates were calculated. Results A total of 1 144 specimens were collected. There were 698 cases with HPV infections,and the infection rate was 61.0%. The 23 subtypes had been determined. The subtype with the highest infection rate was high-risk type 52（16.5%）,followed by type 16（14.5%） and type 58（7.1%）. Single subtype infection rate was 36.5%,and multiple infection rate was 24.5%. The determination rates of ≤25,26-35,36-45,46-55 and >55 years old groups were 56.4%,61.8%,59.9%,63.3% and 57.4%,respectively. Conclusions HPV infections in Tongling are mainly single infection and high-risk infection,and the subtype with the highest infection rate is high-risk type 52. The infection rates with different ages are slightly different.

Key words: Human papilloma virus, Subtypes, Cervical diseases