Laboratory Medicine ›› 2025, Vol. 40 ›› Issue (6): 601-605.DOI: 10.3969/j.issn.1673-8640.2025.06.015
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Received:2024-12-19
Revised:2025-04-16
Online:2025-06-30
Published:2025-07-01
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| 组别 | 例数 | 性别 | 年龄/岁 | MRV/fL | MCV/fL | |
|---|---|---|---|---|---|---|
| 男性/[例(%)] | 女性/[例(%)] | |||||
| IDA组 | 110 | 8(7.3) | 102(92.7) | 40.79±13.93 | 85.60(71.40,98.95)*# | 71.80(64.65,77.83)*# |
| 非IDA组 | 107 | 36(33.6) | 71(66.4) | 43.87±17.76 | 109.50(100.30,119.8) | 92.80(83.50,100.9) |
| 健康对照组 | 102 | 37(36.3) | 65(63.7) | 42.58±11.39 | 100.60(98.50,103.6) | 90.75(88.25,92.90) |
| 统计值 | 75.00 | 1.21 | 106.70 | 115.90 | ||
| P值 | <0.000 1 | 0.299 0 | <0.000 1 | <0.000 1 | ||
| 组别 | MCH/pg | MCHC/(g·L-1) | HCT/% | Hb/(g·L-1) | ||
| IDA组 | 21.40(18.68,24.43)*# | 301.0(283.0,315.0)*# | 29.20(24.55,32.20)* | 88.00(71.00,99.25)*# | ||
| 非IDA组 | 30.80(26.60,32.80) | 326.0(314.0,333.0)* | 29.90(23.60,32.70)* | 95.00(76.00,106.00)* | ||
| 健康对照组 | 31.05(30.38,31.93) | 343.0(338.0,347.0) | 44.50(39.58,47.05) | 153.00(133.80,162.00) | ||
| 统计值 | 157.00 | 226.70 | 266.70 | 340.60 | ||
| P值 | <0.000 1 | <0.000 1 | <0.000 1 | <0.000 1 | ||
| 组别 | 血清铁/(μmol·L-1) | TIBC/(μmol·L-1) | FER/(ng·mL-1) | TS/% | ||
| IDA组 | 3.70(2.58,4.83)*# | 77.90(69.48,83.98)*# | 3.00(2.30,4.53)*# | 4.95(3.00,6.73)*# | ||
| 非IDA组 | 13.80(11.30,18.20)* | 59.60(53.40,69.30) | 15.00(9.100,20.10)* | 25.40(18.50,29.65)* | ||
| 健康对照组 | 19.50(15.38,24.33) | 58.30(54.45,63.03) | 120.20(55.48,220.4) | 32.85(26.48,42.65) | ||
| 统计值 | 180.5 | 91.550 | 101.90 | 181.70 | ||
| P值 | <0.000 1 | <0.000 1 | <0.000 1 | <0.000 1 | ||
| 组别 | 例数 | 性别 | 年龄/岁 | MRV/fL | MCV/fL | |
|---|---|---|---|---|---|---|
| 男性/[例(%)] | 女性/[例(%)] | |||||
| IDA组 | 110 | 8(7.3) | 102(92.7) | 40.79±13.93 | 85.60(71.40,98.95)*# | 71.80(64.65,77.83)*# |
| 非IDA组 | 107 | 36(33.6) | 71(66.4) | 43.87±17.76 | 109.50(100.30,119.8) | 92.80(83.50,100.9) |
| 健康对照组 | 102 | 37(36.3) | 65(63.7) | 42.58±11.39 | 100.60(98.50,103.6) | 90.75(88.25,92.90) |
| 统计值 | 75.00 | 1.21 | 106.70 | 115.90 | ||
| P值 | <0.000 1 | 0.299 0 | <0.000 1 | <0.000 1 | ||
| 组别 | MCH/pg | MCHC/(g·L-1) | HCT/% | Hb/(g·L-1) | ||
| IDA组 | 21.40(18.68,24.43)*# | 301.0(283.0,315.0)*# | 29.20(24.55,32.20)* | 88.00(71.00,99.25)*# | ||
| 非IDA组 | 30.80(26.60,32.80) | 326.0(314.0,333.0)* | 29.90(23.60,32.70)* | 95.00(76.00,106.00)* | ||
| 健康对照组 | 31.05(30.38,31.93) | 343.0(338.0,347.0) | 44.50(39.58,47.05) | 153.00(133.80,162.00) | ||
| 统计值 | 157.00 | 226.70 | 266.70 | 340.60 | ||
| P值 | <0.000 1 | <0.000 1 | <0.000 1 | <0.000 1 | ||
| 组别 | 血清铁/(μmol·L-1) | TIBC/(μmol·L-1) | FER/(ng·mL-1) | TS/% | ||
| IDA组 | 3.70(2.58,4.83)*# | 77.90(69.48,83.98)*# | 3.00(2.30,4.53)*# | 4.95(3.00,6.73)*# | ||
| 非IDA组 | 13.80(11.30,18.20)* | 59.60(53.40,69.30) | 15.00(9.100,20.10)* | 25.40(18.50,29.65)* | ||
| 健康对照组 | 19.50(15.38,24.33) | 58.30(54.45,63.03) | 120.20(55.48,220.4) | 32.85(26.48,42.65) | ||
| 统计值 | 180.5 | 91.550 | 101.90 | 181.70 | ||
| P值 | <0.000 1 | <0.000 1 | <0.000 1 | <0.000 1 | ||
| 项目 | 单因素回归分析 | 多因素回归分析 | |||
|---|---|---|---|---|---|
| OR值(95%CI) | P值 | OR值(95%CI) | P值 | ||
| MRV | 0.91(0.89~0.94) | <0.001 | 0.94(0.90~0.98) | <0.001 | |
| MCV | 0.89(0.87~0.92) | <0.001 | 1.34(0.73~2.48) | 0.350 | |
| MCH | 0.74(0.68~0.79) | <0.001 | 0.30(0.04~2.14) | 0.230 | |
| MCHC | 0.92(0.90~0.94) | <0.001 | 1.07(0.91~1.26) | 0.420 | |
| HCT | 1.02(0.98~1.06) | 0.420 | |||
| Hb | 0.99(0.98~1.01) | 0.200 | |||
| 血清铁 | 0.67(0.60~0.74) | <0.001 | 1.52(0.77~3.00) | 0.230 | |
| TIBC | 1.12(1.09~1.16) | <0.001 | 0.96(0.88~1.04) | 0.310 | |
| FER | 0.98(0.93~1.94) | <0.001 | 1.02(0.96~1.09) | 0.470 | |
| TS | 0.79(0.75~0.84) | <0.001 | 0.61(0.39~0.98) | 0.040 | |
| 项目 | 单因素回归分析 | 多因素回归分析 | |||
|---|---|---|---|---|---|
| OR值(95%CI) | P值 | OR值(95%CI) | P值 | ||
| MRV | 0.91(0.89~0.94) | <0.001 | 0.94(0.90~0.98) | <0.001 | |
| MCV | 0.89(0.87~0.92) | <0.001 | 1.34(0.73~2.48) | 0.350 | |
| MCH | 0.74(0.68~0.79) | <0.001 | 0.30(0.04~2.14) | 0.230 | |
| MCHC | 0.92(0.90~0.94) | <0.001 | 1.07(0.91~1.26) | 0.420 | |
| HCT | 1.02(0.98~1.06) | 0.420 | |||
| Hb | 0.99(0.98~1.01) | 0.200 | |||
| 血清铁 | 0.67(0.60~0.74) | <0.001 | 1.52(0.77~3.00) | 0.230 | |
| TIBC | 1.12(1.09~1.16) | <0.001 | 0.96(0.88~1.04) | 0.310 | |
| FER | 0.98(0.93~1.94) | <0.001 | 1.02(0.96~1.09) | 0.470 | |
| TS | 0.79(0.75~0.84) | <0.001 | 0.61(0.39~0.98) | 0.040 | |
| MRV | 模型1 | 模型2 | 模型3 | |||||
|---|---|---|---|---|---|---|---|---|
| OR值(95%CI) | P值 | OR值(95%CI) | P值 | OR值(95%CI) | P值 | |||
| > 99.0 fL | 1 | 1 | 1 | |||||
| ≤ 99.0 fL | 12.42(6.54~23.59) | <0.001 | 15.68(6.97~35.24) | <0.001 | 8.48(1.62~44.46) | 0.011 | ||
| MRV | 模型1 | 模型2 | 模型3 | |||||
|---|---|---|---|---|---|---|---|---|
| OR值(95%CI) | P值 | OR值(95%CI) | P值 | OR值(95%CI) | P值 | |||
| > 99.0 fL | 1 | 1 | 1 | |||||
| ≤ 99.0 fL | 12.42(6.54~23.59) | <0.001 | 15.68(6.97~35.24) | <0.001 | 8.48(1.62~44.46) | 0.011 | ||
| 项目 | AUC(95%CI) | 最佳临界值 | 敏感性/% | 特异性/% |
|---|---|---|---|---|
| MRV | 0.874 4(0.825 1~0.918 0) | 98.5 fL | 84.11 | 80.00 |
| MCV | 0.854 3(0.801 7~0.906 9) | 79.2 fL | 78.50 | 79.09 |
| MCH | 0.866 7(0.818 4~0.915 0) | 25.1 pg | 77.57 | 79.09 |
| MCHC | 0.837 3(0.785 7~0.888 8) | 314.5 g·L-1 | 72.90 | 74.55 |
| HCT | 0.500 3(0.422 4~0.578 3) | 29.4% | 51.40 | 50.91 |
| Hb | 0.576 9(0.499 9~0.653 9) | 90.5 g·L-1 | 56.07 | 60.91 |
| FER | 0.868 6(0.813 1~0.924 0) | 7.5 ng·mL-1 | 79.44 | 84.55 |
| TIBC | 0.839 0(0.784 8~0.893 1) | 68.5 μmol·L-1 | 74.77 | 79.09 |
| 血清铁 | 0.867 3(0.810 6~0.824 0) | 6.2 μmol·L-1 | 83.18 | 83.64 |
| TS | 0.873 1(0.817 4~0.928 8) | 9.6% | 83.18 | 85.45 |
| 血清铁+FER+TIBC | 0.881 2(0.828 5~0.934 0) | 0.62 | 86.92 | 88.18 |
| MRV+血清铁+FER+TIBC | 0.944 9(0.915 5~0.974 2) | 0.60 | 88.79 | 90.91 |
| 项目 | AUC(95%CI) | 最佳临界值 | 敏感性/% | 特异性/% |
|---|---|---|---|---|
| MRV | 0.874 4(0.825 1~0.918 0) | 98.5 fL | 84.11 | 80.00 |
| MCV | 0.854 3(0.801 7~0.906 9) | 79.2 fL | 78.50 | 79.09 |
| MCH | 0.866 7(0.818 4~0.915 0) | 25.1 pg | 77.57 | 79.09 |
| MCHC | 0.837 3(0.785 7~0.888 8) | 314.5 g·L-1 | 72.90 | 74.55 |
| HCT | 0.500 3(0.422 4~0.578 3) | 29.4% | 51.40 | 50.91 |
| Hb | 0.576 9(0.499 9~0.653 9) | 90.5 g·L-1 | 56.07 | 60.91 |
| FER | 0.868 6(0.813 1~0.924 0) | 7.5 ng·mL-1 | 79.44 | 84.55 |
| TIBC | 0.839 0(0.784 8~0.893 1) | 68.5 μmol·L-1 | 74.77 | 79.09 |
| 血清铁 | 0.867 3(0.810 6~0.824 0) | 6.2 μmol·L-1 | 83.18 | 83.64 |
| TS | 0.873 1(0.817 4~0.928 8) | 9.6% | 83.18 | 85.45 |
| 血清铁+FER+TIBC | 0.881 2(0.828 5~0.934 0) | 0.62 | 86.92 | 88.18 |
| MRV+血清铁+FER+TIBC | 0.944 9(0.915 5~0.974 2) | 0.60 | 88.79 | 90.91 |
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