Abstract:

Objective To investigate the role of UroQuick rapid urine culture technique for urinary tract infection（UTI） in children. Methods A total of 235 clean midstream urine samples were collected from children with suspected UTI aged 0-14 years from December 2019 to January 2020. Conventional urine culture and UroQuick rapid urine culture were performed simultaneously. Taking the results of conventional urine culture as gold standard,the diagnostic efficacy of UroQuick rapid urine culture for UTI was further evaluated. Results Among the 235 samples,58（24.7%） samples,including 43 samples of bacteria,4 samples of fungi and 11 samples of bacteria and fungi,were positive by conventional urine culture,while 69 samples,including 55 samples of bacteria,3 samples of fungi and 11 samples of bacteria and fungi,were positive by UroQuick rapid urine culture. The consistency rate of the 2 methods was 86.8%（204/235）. Compared to conventional urine culture,the sensitivity,specificity,positive predictive value and negative predictive value of turbidity value of UroQuick rapid urine culture were 84.48%,88.70%,71.01% and 94.58%,respectively. Furthermore,the sensitivity,specificity,positive predictive value and negative predictive value of bacterial concentration of UroQuick rapid urine culture were 82.76%,92.66%,78.69% and 94.25%,respectively. Conclusions UroQuick rapid urine culture is a new technique for urine culture and has high specificity and negative predictive value whether in turbidity value or in bacterial concentration,which will provide a reference for the early screening of UTI in children.

Key words: Urinary tract infection, Urine culture, UroQuick rapid urine culture, Children