Laboratory Medicine ›› 2022, Vol. 37 ›› Issue (4): 374-376.DOI: 10.3969/j.issn.1673-8640.2022.04.014
Previous Articles Next Articles
Received:
2020-10-17
Revised:
2022-01-16
Online:
2022-04-30
Published:
2022-06-07
CLC Number:
Add to citation manager EndNote|Ris|BibTeX
URL: https://www.shjyyx.com/EN/10.3969/j.issn.1673-8640.2022.04.014
组别 | 例数 | NLR | PLR |
---|---|---|---|
正常对照组 | 51 | 1.64 (1.27,1.89) | 6.70 (5.87,7.93) |
胃癌组 | 68 | 2.16 (1.42,4.71)* | 6.42 (4.36,9.66) |
结直肠癌组 | 90 | 2.26 (1.53,3.84)* | 6.72 (4.56,10.06) |
胰腺癌组 | 28 | 2.30 (1.59,3.56)* | 7.11 (4.74,12.69) |
组别 | 例数 | NLR | PLR |
---|---|---|---|
正常对照组 | 51 | 1.64 (1.27,1.89) | 6.70 (5.87,7.93) |
胃癌组 | 68 | 2.16 (1.42,4.71)* | 6.42 (4.36,9.66) |
结直肠癌组 | 90 | 2.26 (1.53,3.84)* | 6.72 (4.56,10.06) |
胰腺癌组 | 28 | 2.30 (1.59,3.56)* | 7.11 (4.74,12.69) |
组别 | 例数 | NLR | PLR |
---|---|---|---|
正常对照组 | 51 | 1.64 (1.27,1.89)* | 6.70 (5.87,7.93)* |
非转移组 | 69 | 1.84 (1.31,2.44)* | 5.21 (4.51,7.39)* |
转移组 | 109 | 2.65 (1.75,4.71) | 7.5 (4.63,11.82) |
组别 | 例数 | NLR | PLR |
---|---|---|---|
正常对照组 | 51 | 1.64 (1.27,1.89)* | 6.70 (5.87,7.93)* |
非转移组 | 69 | 1.84 (1.31,2.44)* | 5.21 (4.51,7.39)* |
转移组 | 109 | 2.65 (1.75,4.71) | 7.5 (4.63,11.82) |
组别 | 例数 | NLR | PLR |
---|---|---|---|
正常对照组 | 51 | 1.64 (1.27,1.89)* | 6.70 (5.87,7.93)* |
Ⅰ~Ⅱ期组 | 29 | 1.65 (1.01,1.97)* | 4.75 (4.13,6.18) |
Ⅲ期组 | 43 | 1.94 (1.43,2.53)* | 6.1 (4.66,7.66) |
Ⅳ期组 | 106 | 2.89 (1.85,4.86) | 7.63 (4.66,13.15) |
组别 | 例数 | NLR | PLR |
---|---|---|---|
正常对照组 | 51 | 1.64 (1.27,1.89)* | 6.70 (5.87,7.93)* |
Ⅰ~Ⅱ期组 | 29 | 1.65 (1.01,1.97)* | 4.75 (4.13,6.18) |
Ⅲ期组 | 43 | 1.94 (1.43,2.53)* | 6.1 (4.66,7.66) |
Ⅳ期组 | 106 | 2.89 (1.85,4.86) | 7.63 (4.66,13.15) |
[1] |
BEDEIR A, KRASINSKAS A M. Molecular diagnostics of colorectal cancer[J]. Arch Pathol Lab Med, 2011, 135(5):578-587.
DOI URL |
[2] | GAO G D, SUN B, WANG X B, et al. Neutrophil to lymphocyte ratio as prognostic indicator for patients with esophageal squamous cell cancer[J]. Int J Biol Markers, 2017, 32(4):e409-e414. |
[3] |
MIAO C, ZHU S, PAN H, et al. Combined neutrophil-platelet score and hemoglobin level predict survival in esophageal squamous cell carcinoma patients treated with chemoradiotherapy[J]. Oncotarget, 2017, 8(50):87971-87979.
DOI URL |
[4] | FENG J F, HUANG Y, ZHAO Q, et al. Clinical significance of preoperative neutrophil lymphocyte ratio versus platelet lymphocyte ratio in patients with small cell carcinoma of the esophagus[J]. Scientific World Journal, 2013, 2013:504365. |
[5] |
MARNETT L J. Oxyradicals and DNA damage[J]. Carcinogenesis, 2000, 21(3):361-370.
DOI URL |
[6] |
MCDONALD B, SPICER J, GIANNAIS B, et al. Systemic inflammation increases cancer cell adhesion to hepatic sinusoids by neutrophil mediated mechanisms[J]. Int J Cancer, 2009, 125(6):1298-1305.
DOI URL |
[7] | ITZKOWITZ S H, YIO X. Inflammation and cancer Ⅳ. Colorectal cancer in inflammatory bowel disease:the role of inflammation[J]. Am J Physiol Gastrointest Liver Physiol, 2004, 287(1):G7-G17. |
[8] | TECCHIO C, CASSATELLA M A. Neutrophil-derived cytokines involved in physiological and pathological angiogenesis[J]. Chem Immunol Allergy, 2014, 99:123-137. |
[9] |
SPICER J D, MCDONALD B, COOLS-LARTIGUE J J, et al. Neutrophils promote liver metastasis via Mac-1-mediated interactions with circulating tumor cells[J]. Cancer Res, 2012, 72(16):3919-3927.
DOI URL |
[10] | KURT M, ONAL I K, SAYILIR A Y, et al. The role of mean platelet volume in the diagnosis of hepatocellular carcinoma in patients with chronic liver disease[J]. Hepatogastroenterology, 2012, 59(117):1580-1582. |
[11] |
WANG Z, JIN H, XU R, et al. Triptolide downregulates Rac1 and the JAK/STAT3 pathway and inhibits colitis-related colon cancer progression[J]. Exp Mol Med, 2009, 41(10):717-727.
DOI URL |
[12] | TANG H, LI B, ZHANG A, et al. Significance of neutrophil-to-lymphocyte ratio in colorectal liver metastasis:a systematic review and meta-analysis[J]. PLoS One, 2016, 11(7):e0159447. |
[13] | CERWENKA A, LANIER L L. Natural killer cell memory in infection,inflammation and cancer[J]. Nat Rev Immunol, 2016, 16(2):121-123. |
[14] | URIBE-QUEROL E, ROSALES C. Neutrophils in cancer:two sides of the same coin[J]. J Immunol Res, 2015, 2015:983698. |
[15] |
MEZOUAR S, FRÈRE C, DARBOUSSET R, et al. Role of platelets in cancer and cancer-associated thrombosis:experimental and clinical evidences[J]. Thromb Res, 2016, 139:65-76.
DOI URL |
[16] | ZHANG Y, LU J J, DU Y P, et al. Prognostic value of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio in gastric cancer[J]. Medicine(Baltimore), 2018, 97(12):e0144. |
[17] |
YING H Q, DENG Q W, HE B S, et al. The prognostic value of preoperative NLR,d-NLR,PLR and LMR for predicting clinical outcome in surgical colorectal cancer patients[J]. Med Oncol, 2014, 31(12):305.
DOI URL |
[1] | FAN Lieying. Research status and application prospects of biomarkers for membranous nephropathy [J]. Laboratory Medicine, 2023, 38(12): 1111-1114. |
[2] | SUN Lincheng, LI Jianfeng, CHENG Weili, JI Panyun. Roles of anti-PLA2R IgG4 antibody and PLA2R IgG4/IgG ratio in primary membranous nephropathy [J]. Laboratory Medicine, 2023, 38(12): 1115-1120. |
[3] | LIU Qingyang, YUAN Jianming, XIA Jinjun, JIANG Fengying, WANG Qiubo, WANG Xiaoming. CXCL9 as a potential diagnostic marker of rheumatoid arthritis based on GEO database and experimental verification [J]. Laboratory Medicine, 2023, 38(12): 1121-1129. |
[4] | YANG Xiao, LI Enling, WU Lixia, DAI Yingxin, WANG Zhiqing, HUANG Hao, ZHENG Bing. Influence of cytoplasmic antinuclear antibody on indirect immunofluorescence assay based antineutrophil cytoplasmic antibody determination [J]. Laboratory Medicine, 2023, 38(12): 1135-1140. |
[5] | XIANG Jin, LIU Aiping, HU Yao, WU Zhiyuan, CAO Guojun, GUAN Ming. ANA profiles in COVID-19 patients and influence of serum heat-inactivation on ANA determination [J]. Laboratory Medicine, 2023, 38(12): 1141-1146. |
[6] | CHENG Yu, XU Zhen, LU Liu, DING Menglei, YU Shanshan, ZONG Ming, FAN Lieying. Expression and risk factors of anti-ACE-2 antibody in serum of patients with COVID-19 [J]. Laboratory Medicine, 2023, 38(12): 1147-1152. |
[7] | . [J]. Laboratory Medicine, 2023, 38(12): 1153-1156. |
[8] | . [J]. Laboratory Medicine, 2023, 38(12): 1157-1159. |
[9] | WANG Hongling, LIU Mengna, BAI Ping, LIAO Huanjin. Risk factors of relapse following allogeneic hematopoietic stem cell transplantation in patients with acute myeloid leukemia [J]. Laboratory Medicine, 2023, 38(12): 1160-1166. |
[10] | YANG Xilan, WANG Jinyu, LIU Shuyu, ZHAN Yiyang, LIU Jing, JIA Jian. Correlation between hyperlipidemia and endothelial microparticles in elderly patients from Gulou Community in Nanjing [J]. Laboratory Medicine, 2023, 38(12): 1167-1172. |
[11] | DAI Fangfang, LU Xinxin, YU Yanhua, CHEN Ming, SUN Guizhen. Analysis of Mycobacterium infection in HIV/AIDS patients [J]. Laboratory Medicine, 2023, 38(12): 1173-1176. |
[12] | GU Yu, LIANG Xiaoyan, MA Shenghui, TONG Na, CHENG Mingyan, YAN Zejun. Expression and near-term prognostic predictive value of plasma biomarkers in chronic kidney disease patients with thromboembolism [J]. Laboratory Medicine, 2023, 38(12): 1177-1182. |
[13] | . [J]. Laboratory Medicine, 2023, 38(12): 1183-1185. |
[14] | . [J]. Laboratory Medicine, 2023, 38(12): 1186-1190. |
[15] | . [J]. Laboratory Medicine, 2023, 38(12): 1191-1194. |
Viewed | ||||||
Full text |
|
|||||
Abstract |
|
|||||