Abstract:

Objective To investigate the distribution characteristics of peripheral blood neutrophil-to-lymphocyte ratio（NLR），platelet-to-lymphocyte ratio（PLR） and lymphocyte-to-monocyte ratio（LMR） of healthy adults in Xi’an. Methods A total of 6 835 healthy adults were enrolled from Shaanxi Provincial People’s Hospital from January 2021 to December 2021，and routine blood test was performed. After excluding outliers，6 781 research subjects were enrolled. They were classified according to sex and ages [young（18-44-year-old），middle-aged（45-59-year-old） and elder（>59-year-old） groups]. The differences of NLR，PLR and LMR were evaluated. Results There was statistical significance of NLR，PLR and LMR for different age groups（P<0.05）. For males，there was statistical significance for NLR between young group and middle-aged，elder groups（P<0.05），there was statistical significance for PLR between elder group and young，middle-aged groups（P<0.05），and there was statistical significance for LMR among the 3 age groups（P<0.05）. For females，there was no statistical significance for NLR and LMR among the 3 age groups（P>0.05），and there was statistical significance for PLR among the 3 age groups（P<0.05）. Conclusions NLR，PLR and LMR are different in the population of different sex and age groups in Xi’an. The clinical diagnosis of related diseases should be based on the actual distribution characteristics of NLR，PLR and LMR.

Key words: Neutrophil-to-lymphocyte ratio, Platelet-to-lymphocyte ratio, Lymphocyte-to-monocyte ratio, Healthy adult, Xi’an