Laboratory Medicine ›› 2021, Vol. 36 ›› Issue (9): 985-987.DOI: 10.3969/j.issn.1673-8640.2021.09.021
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Received:
2020-10-31
Online:
2021-09-30
Published:
2021-09-24
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URL: https://www.shjyyx.com/EN/10.3969/j.issn.1673-8640.2021.09.021
组别 | 例数 | CKD病程/年 | LVEF/% | SV/mL | SCr/ (μmol/L) | Cys C/ (mg/L) | NT-proBNP / (pg/mL) |
---|---|---|---|---|---|---|---|
正常对照组 | 50 | 57.22±5.14 | 63.78±5.54 | 92.21±21.09 | 0.78±0.12 | 737.62±520.17 | |
CKD无CHF组 | 66 | 6.85±3.12 | 50.93±5.65* | 54.93±5.45* | 332.18±45.79* | 1.66±0.38* | 1 224.32±688.92* |
CKD合并CHF 组 | 54 | 7.02±3.68 | 41.31±4.24*# | 51.31±5.08*# | 554.56±42.33*# | 2.97±0.45*# | 2 144.50±654.33*# |
统计值 | 1.10 | 156.20 | 83.48 | 1 831.28 | 581.13 | 78.74 | |
P值 | 0.335 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
组别 | 例数 | CKD病程/年 | LVEF/% | SV/mL | SCr/ (μmol/L) | Cys C/ (mg/L) | NT-proBNP / (pg/mL) |
---|---|---|---|---|---|---|---|
正常对照组 | 50 | 57.22±5.14 | 63.78±5.54 | 92.21±21.09 | 0.78±0.12 | 737.62±520.17 | |
CKD无CHF组 | 66 | 6.85±3.12 | 50.93±5.65* | 54.93±5.45* | 332.18±45.79* | 1.66±0.38* | 1 224.32±688.92* |
CKD合并CHF 组 | 54 | 7.02±3.68 | 41.31±4.24*# | 51.31±5.08*# | 554.56±42.33*# | 2.97±0.45*# | 2 144.50±654.33*# |
统计值 | 1.10 | 156.20 | 83.48 | 1 831.28 | 581.13 | 78.74 | |
P值 | 0.335 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
CKD分期 | 例数 | SCr/(μmol/L) | Cys C/(mg/L) | NT-proBNP/(pg/mL) |
---|---|---|---|---|
CKD1期 | 18 | 101.34±26.92 | 1.01±0.21 | 675.61±381.73 |
CKD2~3期 | 15 | 345.56±22.83* | 1.64±0.28* | 1 133.17±433.56* |
CKD4~5期 | 21 | 626.83±34.05*# | 2.75±0.38*# | 1 525.68±512.44*# |
F值 | 1 604.11 | 163.52 | 17.24 | |
P值 | <0.001 | <0.001 | <0.001 |
CKD分期 | 例数 | SCr/(μmol/L) | Cys C/(mg/L) | NT-proBNP/(pg/mL) |
---|---|---|---|---|
CKD1期 | 18 | 101.34±26.92 | 1.01±0.21 | 675.61±381.73 |
CKD2~3期 | 15 | 345.56±22.83* | 1.64±0.28* | 1 133.17±433.56* |
CKD4~5期 | 21 | 626.83±34.05*# | 2.75±0.38*# | 1 525.68±512.44*# |
F值 | 1 604.11 | 163.52 | 17.24 | |
P值 | <0.001 | <0.001 | <0.001 |
项目 | 回归系数 | P值 | HR①值 (95%可信区间) |
---|---|---|---|
住院死亡 | 0.21 | <0.001 | 1.23(1.13~1.45) |
出院后30 d死亡 | 0.11 | 0.012 | 1.12(1.08~1.15) |
3个月内再住院 | 0.29 | <0.001 | 1.34(1.30~1.68) |
项目 | 回归系数 | P值 | HR①值 (95%可信区间) |
---|---|---|---|
住院死亡 | 0.21 | <0.001 | 1.23(1.13~1.45) |
出院后30 d死亡 | 0.11 | 0.012 | 1.12(1.08~1.15) |
3个月内再住院 | 0.29 | <0.001 | 1.34(1.30~1.68) |
[1] |
CHEN T K, KNICELY D H, GRAMS M E. Chronic kidney disease diagnosis and management:a review[J]. JAMA, 2019, 322(13):1294-1304.
DOI URL |
[2] | 上海慢性肾脏病早发现及规范化诊治与示范项目专家组. 慢性肾脏病筛查诊断及防治指南[J]. 中国实用内科杂志, 2017, 37(1):28-34. |
[3] |
DELANAYE P, JAGER K J, BÖKENKAMP A, et al. CKD:a call for an age-adapted definition[J]. J Am Soc Nephrol, 2019, 30(10):1785-1805.
DOI URL |
[4] | 伊双燕, 骆雷鸣, 付士辉, 等. 高龄严重急性失代偿性心力衰竭患者发生肾功能恶化的影响因素分析及肾功能恶化对其预后的预测价值研究[J]. 中国全科医学, 2018, 21(18):2167-2172. |
[5] |
CAO Z, JIA Y, ZHU B. BNP and NT-proBNP as diagnostic biomarkers for cardiac dysfunction in both clinical and forensic medicine[J]. Int J Mol Sci, 2019, 20(8):1820.
DOI URL |
[6] |
TEO B W, ZHANG L, GUH J Y, et al. Glomerular filtration rates in Asians[J]. Adv Chronic Kidney Dis, 2018, 25(1):41-48.
DOI URL |
[7] |
GROMADZINSKI L, JANUSZKO-GIERGIELEWICZ B, CZARNACKA K, et al. NT-proBNP in the prognosis of death or need for renal replacement therapy in patients with stage 3-5 chronic kidney disease[J]. Cardiorenal Med, 2019, 9(2):125-134.
DOI URL |
[8] |
PETRA E, ZOIDAKIS J, VLAHOU A. Protein biomarkers for cardiorenal syndrome[J]. Expert Rev Proteomics, 2019, 16(4):325-336.
DOI URL |
[9] |
CHARMETANT X, PECQUET M, POIRIÉ P, et al. Impact of age and renal function on usefulness of NT-proBNP to diagnose heart failure[J]. Clin Nephrol, 2019, 92(2):65-72.
DOI URL |
[10] |
BANSAL N, ZALNICK L, SHLPAK M G, et al. Cardiac and stress biomarkers and chronic kidney disease progression:the CRIC study[J]. Clin Chem, 2019, 65(11):1448-1457.
DOI URL |
[11] |
GAO P, ZHU Q, BIAN S, et al. Prognostic value of plasma NT-proBNP levels in very old patients with moderate renal insufficiency in China[J]. Z Gerontol Geriatr, 2018, 51(8):889-896.
DOI URL |
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