Laboratory Medicine ›› 2020, Vol. 35 ›› Issue (12): 1310-1314.DOI: 10.3969/j.issn.1673-8640.2020.12.026

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Evolutionary tree and its application in the analysis of bacterial kinship

CHI Wenjing, LIU Yixin, WANG Su, LIU Tao, ZHAO Hu, ZHANG Yanmei()   

  1. Department of Clinical Laboratory,Huadong Hospital,Fudan University,Shanghai 20004,China
  • Received:2019-04-22 Online:2020-12-30 Published:2020-12-31

Abstract:

As the development and application of biological technology,many unknown bacteria have been identified gradually. Meanwhile,with environment changing,some known pathogenic bacteria have evolved new phenotypes involved in pathopoiesia or resistance. In the face of growing threats,carrying out research in bacteria evolution and its relationship with classical pathogens and exploring the emerging mechanisms of new pathogen or new phenotypes would provide a reference for the prevention and controlling of pathogens. Because the genome carries all the genetic information of a species,the research based on the bacterial genome analysis would present a more realistic evolutionary process. Especially,the development of the molecular biotechnology,such as sequencing,will provide powerful tools for understanding the evolutionary process and mechanisms and their genetic traits and functional characteristics of bacteria.

Key words: Bacterium, Evolutionary tree, Genome, Phylogeny

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