Laboratory Medicine ›› 2018, Vol. 33 ›› Issue (11): 1036-1042.DOI: 10.3969/j.issn.1673-8640.2018.011.015

• Orginal Article • Previous Articles     Next Articles

Research progress in the determination methods of tumor markers

ZHANG Yingcong1, ZHANG Ze1, YU Hongwei1, SANG Zhuoqi2, CHANG Dong1   

  1. 1. Department of Clinical Laboratory,Shanghai Pudong Hospital,Fudan University,Shanghai 201399,China
    2. Department of Clinical Laboratory,Shanghai Punan Hospital of Pudong New Aera,Shanghai 201399,China
  • Received:2017-11-22 Online:2018-11-30 Published:2018-11-28

Abstract:

Tumor is a serious hidden threat to human health,and the morbidity and mortality rates of the diseases caused by tumors are increasing year by year. Tumor markers are produced by tumor tissues or their host reacts,which can reflect and monitor the occurrence,development,prognosis and recurrence of tumors. Early determination of tumors is important,and monitoring the change of tumor markers is also an important method to evaluate the therapeutic effect of tumors. The common determination methods of tumor markers include immunology,biosensor,proteomics,molecular biology,liquid biopsy and so on. Different determination methods of tumor markers have different characteristics. This review focuses on the research progress of several common determination methods of tumor markers.

Key words: Tumor marker, Determination method, Proteomics

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