Laboratory Medicine ›› 2017, Vol. 32 ›› Issue (9): 760-764.DOI: 10.3969/j.issn.1673-8640.2017.09.004
• Orginal Article • Previous Articles Next Articles
SHANG Lu, SUN Fenyong
Received:
2017-03-26
Online:
2017-09-30
Published:
2017-09-30
CLC Number:
SHANG Lu, SUN Fenyong. Levels of serum homocysteine in middle-aged and elderly people in Dongjing community of Shanghai and their influence factors[J]. Laboratory Medicine, 2017, 32(9): 760-764.
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项目 | 例数 | 百分比(%) | 项目 | 例数 | 百分比(%) | 项目 | 例数 | 百分比(%) | ||
---|---|---|---|---|---|---|---|---|---|---|
BMI(kg/m2) | TC | Hcy | ||||||||
<18.5 | 79 | 3.4 | 正常 | 1 532 | 65.6 | 正常 | 1 984 | 84.9 | ||
18.5~<25.0 | 1 260 | 53.9 | 异常 | 804 | 34.4 | 异常 | 352 | 15.1 | ||
≥25.0 | 997 | 42.7 | Cr | 高血压 | ||||||
收缩压(kPa) | 正常 | 2 175 | 93.1 | 无 | 1 143 | 48.9 | ||||
<15.96 | 375 | 16.1 | 异常 | 161 | 6.9 | 有 | 1 193 | 51.1 | ||
15.96~18.49 | 1 141 | 48.8 | Glu | 糖尿病 | ||||||
≥18.62 | 820 | 35.1 | 正常 | 1 906 | 81.6 | 无 | 1 917 | 82.1 | ||
舒张压(kPa) | 异常 | 430 | 18.4 | 有 | 419 | 17.9 | ||||
<10.64 | 932 | 39.9 | TG | 心脏病 | ||||||
10.64~11.84 | 1 076 | 46.1 | 正常 | 2 059 | 88.1 | 无 | 1 379 | 59.0 | ||
≥11.97 | 328 | 14.0 | 异常 | 277 | 11.9 | 有 | 957 | 41.0 | ||
尿素 | UA | |||||||||
正常 | 2 138 | 91.5 | 正常 | 1 808 | 77.4 | |||||
异常 | 198 | 8.5 | 异常 | 528 | 22.6 |
项目 | 例数 | 百分比(%) | 项目 | 例数 | 百分比(%) | 项目 | 例数 | 百分比(%) | ||
---|---|---|---|---|---|---|---|---|---|---|
BMI(kg/m2) | TC | Hcy | ||||||||
<18.5 | 79 | 3.4 | 正常 | 1 532 | 65.6 | 正常 | 1 984 | 84.9 | ||
18.5~<25.0 | 1 260 | 53.9 | 异常 | 804 | 34.4 | 异常 | 352 | 15.1 | ||
≥25.0 | 997 | 42.7 | Cr | 高血压 | ||||||
收缩压(kPa) | 正常 | 2 175 | 93.1 | 无 | 1 143 | 48.9 | ||||
<15.96 | 375 | 16.1 | 异常 | 161 | 6.9 | 有 | 1 193 | 51.1 | ||
15.96~18.49 | 1 141 | 48.8 | Glu | 糖尿病 | ||||||
≥18.62 | 820 | 35.1 | 正常 | 1 906 | 81.6 | 无 | 1 917 | 82.1 | ||
舒张压(kPa) | 异常 | 430 | 18.4 | 有 | 419 | 17.9 | ||||
<10.64 | 932 | 39.9 | TG | 心脏病 | ||||||
10.64~11.84 | 1 076 | 46.1 | 正常 | 2 059 | 88.1 | 无 | 1 379 | 59.0 | ||
≥11.97 | 328 | 14.0 | 异常 | 277 | 11.9 | 有 | 957 | 41.0 | ||
尿素 | UA | |||||||||
正常 | 2 138 | 91.5 | 正常 | 1 808 | 77.4 | |||||
异常 | 198 | 8.5 | 异常 | 528 | 22.6 |
组别 | 例数 | Hcy(μmol/L) | 高Hcy血症 [例(%)] | 正常Hcy [例(%)] | OR值 (男/女)△ | 95%可信区间 |
---|---|---|---|---|---|---|
55~64岁组 | 678 | 12.24(10.19~14.74) | 148(21.8) | 530(78.2) | ||
男 | 331 | 13.67(11.52~15.83) | 112(33.8)* | 219(66.2) | 4.418 | 2.922~6.680 |
女 | 347 | 11.20(9.29~12.92) | 36(10.4) | 311(89.6) | ||
65~74岁组 | 1 073 | 13.01(10.68~15.67)# | 99(9.2)# | 974(90.77) | ||
男 | 518 | 14.31(12.00~17.14) | 71(13.7)* | 447(86.3) | 2.990 | 1.896~4.713 |
女 | 555 | 12.05(9.88~14.16 | 28(5.0) | 527(95.0) | ||
75~84岁组 | 513 | 14.86(12.29~18.23)# | 86(16.8)# | 427(83.2) | ||
男 | 216 | 16.21(13.56~20.75) | 58(26.9)* | 158(73.1) | 3.527 | 2.156~5.768 |
女 | 297 | 13.57(11.57~16.35) | 28(9.4) | 269(90.6) | ||
≥85岁组 | 72 | 16.85(14.23~20.53)# | 19(26.4)# | 53(73.6) | ||
男 | 29 | 17.87(15.38~22.59) | 11(37.9) | 18(62.1) | 2.674 | 0.914~7.823 |
女 | 43 | 16.13(12.50~18.02) | 8(18.5) | 35(81.5) | ||
合计 | 2 336 | 13.18(10.82~16.00) | 352(15.1) | 1 984(84.9) | 3.418 | 2.667~4.381 |
组别 | 例数 | Hcy(μmol/L) | 高Hcy血症 [例(%)] | 正常Hcy [例(%)] | OR值 (男/女)△ | 95%可信区间 |
---|---|---|---|---|---|---|
55~64岁组 | 678 | 12.24(10.19~14.74) | 148(21.8) | 530(78.2) | ||
男 | 331 | 13.67(11.52~15.83) | 112(33.8)* | 219(66.2) | 4.418 | 2.922~6.680 |
女 | 347 | 11.20(9.29~12.92) | 36(10.4) | 311(89.6) | ||
65~74岁组 | 1 073 | 13.01(10.68~15.67)# | 99(9.2)# | 974(90.77) | ||
男 | 518 | 14.31(12.00~17.14) | 71(13.7)* | 447(86.3) | 2.990 | 1.896~4.713 |
女 | 555 | 12.05(9.88~14.16 | 28(5.0) | 527(95.0) | ||
75~84岁组 | 513 | 14.86(12.29~18.23)# | 86(16.8)# | 427(83.2) | ||
男 | 216 | 16.21(13.56~20.75) | 58(26.9)* | 158(73.1) | 3.527 | 2.156~5.768 |
女 | 297 | 13.57(11.57~16.35) | 28(9.4) | 269(90.6) | ||
≥85岁组 | 72 | 16.85(14.23~20.53)# | 19(26.4)# | 53(73.6) | ||
男 | 29 | 17.87(15.38~22.59) | 11(37.9) | 18(62.1) | 2.674 | 0.914~7.823 |
女 | 43 | 16.13(12.50~18.02) | 8(18.5) | 35(81.5) | ||
合计 | 2 336 | 13.18(10.82~16.00) | 352(15.1) | 1 984(84.9) | 3.418 | 2.667~4.381 |
项目 | 例数 | 高Hcy血症 | 正常Hcy |
---|---|---|---|
BMI(kg/m2) | |||
<18.5组 | 79 | 9(11.4) | 70(88.6) |
18.5~24.99组 | 1 260 | 195(15.6) | 1 059(84.4) |
≥25.0组 | 997 | 148(14.8) | 855(85.2) |
收缩压(kPa) | |||
<15.96组 | 375 | 43(11.5) | 332(88.5) |
15.96~18.49组 | 1 141 | 169(14.8)* | 972(85.2) |
≥18.62组 | 820 | 140(17.1)*# | 680(82.9) |
舒张压(kPa) | |||
<10.64组 | 932 | 134(14.4) | 798(85.6) |
10.64~11.84组 | 1 076 | 165(15.3) | 911(84.7) |
≥11.97组 | 328 | 53(16.2) | 275(83.8) |
项目 | 例数 | 高Hcy血症 | 正常Hcy |
---|---|---|---|
BMI(kg/m2) | |||
<18.5组 | 79 | 9(11.4) | 70(88.6) |
18.5~24.99组 | 1 260 | 195(15.6) | 1 059(84.4) |
≥25.0组 | 997 | 148(14.8) | 855(85.2) |
收缩压(kPa) | |||
<15.96组 | 375 | 43(11.5) | 332(88.5) |
15.96~18.49组 | 1 141 | 169(14.8)* | 972(85.2) |
≥18.62组 | 820 | 140(17.1)*# | 680(82.9) |
舒张压(kPa) | |||
<10.64组 | 932 | 134(14.4) | 798(85.6) |
10.64~11.84组 | 1 076 | 165(15.3) | 911(84.7) |
≥11.97组 | 328 | 53(16.2) | 275(83.8) |
组别 | 例数 | 高Hcy血症 | 正常Hcy |
---|---|---|---|
TG | |||
正常组 | 2 059 | 305(14.8) | 1 754(85.2) |
异常组 | 277 | 47(17.0) | 230(83.0) |
TC | |||
正常组 | 1 532 | 249(16.3)* | 1 283(83.7) |
异常组 | 804 | 103(12.8) | 701(87.2) |
Glu | |||
正常组 | 1 906 | 286(15.0) | 1 620(85.0) |
异常组 | 430 | 66(15.3) | 364(84.7) |
Cr | |||
正常组 | 2 175 | 281(12.9)** | 1 894(87.1) |
异常组 | 161 | 71(44.1) | 90(55.9) |
尿素 | |||
正常组 | 2 138 | 304(14.2)** | 1 834(85.8) |
异常组 | 198 | 48(24.2) | 150(75.8) |
UA | |||
正常组 | 1 808 | 222(12.3)** | 1 586(87.7) |
异常组 | 528 | 130(24.6) | 398(75.4) |
组别 | 例数 | 高Hcy血症 | 正常Hcy |
---|---|---|---|
TG | |||
正常组 | 2 059 | 305(14.8) | 1 754(85.2) |
异常组 | 277 | 47(17.0) | 230(83.0) |
TC | |||
正常组 | 1 532 | 249(16.3)* | 1 283(83.7) |
异常组 | 804 | 103(12.8) | 701(87.2) |
Glu | |||
正常组 | 1 906 | 286(15.0) | 1 620(85.0) |
异常组 | 430 | 66(15.3) | 364(84.7) |
Cr | |||
正常组 | 2 175 | 281(12.9)** | 1 894(87.1) |
异常组 | 161 | 71(44.1) | 90(55.9) |
尿素 | |||
正常组 | 2 138 | 304(14.2)** | 1 834(85.8) |
异常组 | 198 | 48(24.2) | 150(75.8) |
UA | |||
正常组 | 1 808 | 222(12.3)** | 1 586(87.7) |
异常组 | 528 | 130(24.6) | 398(75.4) |
组别 | 例数 | 高Hcy血症 | 正常Hcy |
---|---|---|---|
高血压 | |||
无 | 1 143 | 166(14.5) | 977(85.5) |
有 | 1 193 | 186(15.6) | 1 007(84.4) |
糖尿病 | |||
无 | 1 917 | 279(14.6) | 1 638(85.4) |
有 | 419 | 73(17.4) | 346(82.6) |
心脏病 | |||
无 | 1 379 | 180(13.1)* | 1 199(86.9) |
有 | 957 | 172(18.0) | 785(82.0) |
组别 | 例数 | 高Hcy血症 | 正常Hcy |
---|---|---|---|
高血压 | |||
无 | 1 143 | 166(14.5) | 977(85.5) |
有 | 1 193 | 186(15.6) | 1 007(84.4) |
糖尿病 | |||
无 | 1 917 | 279(14.6) | 1 638(85.4) |
有 | 419 | 73(17.4) | 346(82.6) |
心脏病 | |||
无 | 1 379 | 180(13.1)* | 1 199(86.9) |
有 | 957 | 172(18.0) | 785(82.0) |
变量 | 偏回归系数 | 标准误差 | 自由度 | P值 | 优势比(95%可信区间) |
---|---|---|---|---|---|
男性 | 1.304 | 0.132 | 1 | <0.001 | 3.686(2.846~4.773) |
UA | 0.594 | 0.138 | 1 | <0.001 | 1.812(1.382~2.375) |
Cr | 1.493 | 0.190 | 1 | <0.001 | 4.450(3.067~6.455) |
收缩压 | 0.010 | 0.004 | 1 | 0.013 | 1.010(1.002~1.018) |
心脏病 | 0.305 | 0.124 | 1 | 0.014 | 1.357(1.065~1.729) |
变量 | 偏回归系数 | 标准误差 | 自由度 | P值 | 优势比(95%可信区间) |
---|---|---|---|---|---|
男性 | 1.304 | 0.132 | 1 | <0.001 | 3.686(2.846~4.773) |
UA | 0.594 | 0.138 | 1 | <0.001 | 1.812(1.382~2.375) |
Cr | 1.493 | 0.190 | 1 | <0.001 | 4.450(3.067~6.455) |
收缩压 | 0.010 | 0.004 | 1 | 0.013 | 1.010(1.002~1.018) |
心脏病 | 0.305 | 0.124 | 1 | 0.014 | 1.357(1.065~1.729) |
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