Abstract:

Objective To analyze the indices for lymphangioleiomyomatosis （LAM）,and provide a reference for its diagnosis and treatment. Methods A retrospective analysis was performed for 38 LAM patients. Indices of routine blood tests [white blood cell（WBC）,hemoglobin（Hb） and platelet（PLT）],liver function [alanine aminotransferase（ALT）,aspartate aminotransferase（AST）,total protein（TP） and albumin（Alb）], kidney function [creatinine（Cr）],serum glucose（Glu）,triglyceride（TG）,tumor marker [carbohydrate antigen（CA）125],total complement and blood gas [pH,partial pressure of oxygen（PO₂） and partial pressure of carbon dioxide （PCO₂）] were analyzed. Results In LAM patients,the results of routine blood tests,liver function and kidney function had no significant changes. The results of blood gas showed that LAM patients existed different degrees of acidosis. CA125 of 90.9% LAM patients increased and exceeded the upper limit of reference interval for 3 times to 30 times. Serum total complement of 75.84% LAM patients increased slightly and within 1 time of the upper limit of reference interval. Conclusions CA125 and blood gas results of LAM patients have significant changes.

Key words: Lymphangioleiomyomatosis, Carbohydrate antigen 125, Blood gas, Total complement