Group B Streptococcus screen in prevention and control of maternal and neonatal infection

doi:10.3969/j.issn.1673-8640.2016.04.005

Abstract

Abstract:

Objective To establish a screen method for group B Streptococcus（GBS） in prenatal period,to investigate the significance of GBS screen among pregnant women in late pregnancy,to take interventions to GBS carriers,and to observe prevention and control of maternal and neonatal infection. Methods A total of 1 000 cases with more than 35-week pregnancy for prenatal care and delivery were enrolled,and their samples from vaginal orifice 1/3 and perianal secretions were collected for GBS screen. GBS was detected by bacterial culture method. GBS-positive subjects were classified into intervention and non-intervention groups according to subjects' wishes. Intervention group was treated with prophylactic antibiotics in delivery or rupture of membranes,and non-intervention group was not treated. Maternal pregnancy outcomes were compared. Results A total of 97 cases had GBS infection,and the infection rate was 9.7%. Compared with GBS-negative group,premature rupture of membranes,premature delivery,intrauterine infection,fetal distress,neonatal low quality,Apgar score and infection incidence in intervention group had no statistical significance（P>0.05）. The difference of Apgar score in intervention group had no statistical significance compared with non-intervention group（P>0.05）,and other indices had statistical significance（P<0.05）. Conclusions The screen method for GBS in pregnant women's vaginal and perianal secretions is rapid,sensitive and specific. It is important to carry out GBS screen among pregnant women in late pregnancy. It can effectively reduce the incidence of adverse maternal and neonatal pregnancy outcomes and infection.

Key words: Late pregnancy, Group B Streptococcus, Mother-to-infant infection

CLC Number:

R446.11

CHEN Xiaoping, WANG Huijiao, YU Beiwei, XU Jiaojun, XU Qiulian, ZHAO Lan, XU Xiaobao, DING Mingxing. Group B Streptococcus screen in prevention and control of maternal and neonatal infection[J]. Laboratory Medicine, 2016, 31(4): 266-269.

Figures/Tables 2

References 15

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组别	例数	胎膜早破	早产	宫内感染	胎儿窘迫
干预治疗组	75	6（8.00）	4（5.33）	1（1.33）	8（10.67）
不干预治疗组	22	6（27.27）	5（22.73）	4（18.18）	5（22.73）
GBS对照组	50	3（6.00）	2（4.00）	0（0.00）	4（8.00）

组别	例数	胎膜早破	早产	宫内感染	胎儿窘迫
干预治疗组	75	6（8.00）	4（5.33）	1（1.33）	8（10.67）
不干预治疗组	22	6（27.27）	5（22.73）	4（18.18）	5（22.73）
GBS对照组	50	3（6.00）	2（4.00）	0（0.00）	4（8.00）

组别	例数	低体质量[例（%）]	Apgar评分（分）	感染[例（%）]
干预治疗组	75	2（2.67）	9.25±0.07	5（6.67）
不干预治疗组	22	3（13.64）	8.93±0.05	4（18.18）
GBS对照组	50	1（2.00）	9.57±0.08	3（6.00）

组别	例数	低体质量[例（%）]	Apgar评分（分）	感染[例（%）]
干预治疗组	75	2（2.67）	9.25±0.07	5（6.67）
不干预治疗组	22	3（13.64）	8.93±0.05	4（18.18）
GBS对照组	50	1（2.00）	9.57±0.08	3（6.00）

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