Establishment of biological reference intervals by indirect method

doi:10.3969/j.issn.1673-8640.2015.04.023

Abstract

Abstract:

It is significant for clinical medical laboratories to provide reliable biological reference intervals, which is aimed at guiding proper clinical treatment process. The establishment of biological reference intervals by indirect method which has been arised in recent years has shown great significance in evaluating biological reference intervals periodically within laboratories and establishing biological reference intervals for those projects which cannot be made through direct methods. It is undoubtedly a simple and inexpensive method. This article reviews the basic methods in the process of establishing biological reference intervals by indirect method according to pertinent literatures, which consists of datum acquistion, datum transformation, outlier excluding and reference interval gaining.

Key words: Biological reference interval, Indirect method, Datum transformation, Outlier excluding

CLC Number:

R446.1

SHEN Junfei, SONG Binbin, PAN Baishen.. Establishment of biological reference intervals by indirect method[J]. Laboratory Medicine, 2015, 30(4): 391-396.

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