检验医学 ›› 2017, Vol. 32 ›› Issue (1): 26-29.DOI: 10.3969/j.issn.1673-8640.2017.01.007

• 临床应用研究_论著 • 上一篇    下一篇

血液病患者人附红细胞体感染调查

路凌怡1, 翟元琦2, 王剑飚3   

  1. 1.上海市徐汇区中心医院检验科,上海 200031
    2.上海交通大学医学院检验系,上海 200025
    3.上海交通大学附属瑞金医院检验科,上海 200025
  • 收稿日期:2016-08-09 出版日期:2017-01-20 发布日期:2017-02-10
  • 作者简介:null

    作者简介:路凌怡,男,1988年生,学士,技师,主要从事临床检验工作。

    通信作者:王剑飚,联系电话:021-64370045-60612。

  • 基金资助:
    上海市卫生和计划生育委员会科研课题(201440481)

Eperythrozoon infection in patients with blood diseases

LU Lingyi1, ZHAI Yuanqi2, WANG Jianbiao3   

  1. 1. Department of Clinical Laboratory,Shanghai Xuhui District Central Hospital,Shanghai 200031,China
    2. Faculty of Laboratory Medicine, Shanghai Jiaotong University School of Medicine,Shanghai 200025,China
    3. Department of Clinical Laboratory,Ruijin Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 200025,China
  • Received:2016-08-09 Online:2017-01-20 Published:2017-02-10

摘要:

目的 调查血液病患者中的附红细胞体感染率。方法 选取体检健康者50名,血液病患者223例,用吖啶橙荧光染色法检测附红细胞体,同时依照疾病类型和特点,对血液病患者进一步分组,分析其感染率与血液病的关系。结果 体检组和血液病组用吖啶橙荧光染色法检测附红细胞体阳性率分别为12.00%和28.25%,2个组阳性率有明显差异,血液病组感染率高于体检组;性别间检测阳性率差异无统计学意义(P>0.05);45~65岁年龄段感染附红细胞体比例最高,各年龄段阳性率差异无统计学意义(P>0.05);血液科门诊患者和住院患者附红细胞体感染检测的阳性率差异无统计学意义(P>0.05);血液病组中淋巴瘤患者感染率最高;淋巴瘤患者和其他血液疾病患者附红细胞体感染的阳性率差异有统计学意义(P<0.05);急性髓系白血病和急性淋系白血病患者检测附红细胞体阳性率差异无统计学意义(P>0.05)。结论 附红细胞体感染年龄以45~65岁为主,男女性别感染情况无明显差异,院内感染的情况可能性小。血液病患者尤其是淋巴瘤患者易感染附红细胞体,不同类型的血液病感染情况不同,需在治疗时予以关注。

关键词: 人附红细胞体, 吖啶橙染色, 血液病

Abstract:

Objective To investigate the infection rate of eperythrozoon in patients with blood diseases. Methods A total of 50 healthy subjects and 223 patients with blood diseases were enrolled. Eperythrozoon was determined by acridine staining. The patients with blood diseases were classified according to disease types and characteristics. The relationship between infection rate and blood diseases was analyzed. Results The infection rates in healthy subject group and blood disease group by acridine staining were 12.00% and 28.25%,respectively. The infection rate in blood disease group was higher than that in healthy subject group. No difference of infection rate was found between males and females(P>0.05). People from 45 to 65 years old had the highest infection rate,and the infection rates showed no statistical significance for ages(P>0.05). The infection rates between outpatients from hematology department and inpatients had no statistical significance(P>0.05). The infection rate of patients with lymphoma was the highest in blood disease group. There was statistical significance for the infection rate between patients with lymphoma and patients with other blood diseases(P<0.05). There was no statistical significance between patients with acute myeloid leukemia and patients with acute lymphocyte leukemia(P>0.05). Conclusions Eperythrozoon mostly infects people from 45 to 65 years old,and there is no difference between males and females. Nosocomial infection is less likely to occur. Patients with blood diseases especially with lymphoma are more susceptible than healthy subjects to eperythrozoon. Different types of blood diseases have different infection rates. Thus,attention should be paid during treatment.

Key words: Human eperythrozoon, Acridine staining, Blood diseases

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