Laboratory Medicine ›› 2023, Vol. 38 ›› Issue (4): 382-384.DOI: 10.3969/j.issn.1673-8640.2023.04.016
Previous Articles Next Articles
Received:
2021-10-12
Revised:
2022-10-28
Online:
2023-04-28
Published:
2023-06-21
CLC Number:
Add to citation manager EndNote|Ris|BibTeX
URL: https://www.shjyyx.com/EN/10.3969/j.issn.1673-8640.2023.04.016
组别 | 例数 | rs9275572位点 | rs9275319位点 | |||||
---|---|---|---|---|---|---|---|---|
GG/[例(%)] | AG/[例(%)] | AA/[例(%)] | GG/[例(%)] | AG/[例(%)] | AA/[例(%)] | |||
宫内感染组 | 44 | 26(50.09) | 16(36.36) | 2(4.55) | 24(54.55) | 18(38.10) | 2(4.55) | |
无宫内感染组 | 87 | 34(39.08) | 37(42.53) | 16(18.39) | 26(29.89) | 41(47.13) | 20(22.99) |
组别 | 例数 | rs9275572位点 | rs9275319位点 | |||||
---|---|---|---|---|---|---|---|---|
GG/[例(%)] | AG/[例(%)] | AA/[例(%)] | GG/[例(%)] | AG/[例(%)] | AA/[例(%)] | |||
宫内感染组 | 44 | 26(50.09) | 16(36.36) | 2(4.55) | 24(54.55) | 18(38.10) | 2(4.55) | |
无宫内感染组 | 87 | 34(39.08) | 37(42.53) | 16(18.39) | 26(29.89) | 41(47.13) | 20(22.99) |
组别 | 例数 | 新生儿性别 | 孕产妇年龄 | 孕周 | 孕前吸烟史/[例(%)] | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
男/ [例(%)] | 女/ [例(%)] | <30岁/ [例(%)] | ≥30岁/ [例(%)] | <37周/ [例(%)] | ≥37周/ [例(%)] | ||||||||||
宫内感染组 | 44 | 26(59.09) | 18(40.91) | 24(54.55) | 20(45.45) | 25(56.82) | 19(43.18) | 5(11.36) | |||||||
无宫内感染组 | 87 | 50(57.47) | 37(42.53) | 46(52.87) | 41(47.13) | 48(55.17) | 39(44.83) | 5(5.75) | |||||||
χ2值 | 0.031 | 0.033 | 0.032 | 1.307 | |||||||||||
P值 | 0.859 | 0.856 | 0.858 | 0.253 | |||||||||||
组别 | 孕前饮酒史/[例(%)] | 孕前3个月感冒史/[例(%)] | 分娩方式 | 孕前体重指数 | 胎盘HBsAg阳性/[例(%)] | ||||||||||
顺产/[例(%)] | 剖宫产/[例(%)] | ≤24 kg/m2/[例(%)] | >24 kg/m2/[例(%)] | ||||||||||||
宫内感染组 | 8(18.18) | 18(40.91) | 29(65.91) | 15(34.09) | 24(54.55) | 20(45.45) | 36(81.82) | ||||||||
无宫内感染组 | 12(13.79) | 7(8.05) | 51(58.62) | 36(41.38) | 63(72.41) | 24(27.59) | 12(13.79) | ||||||||
χ2值 | 0.435 | 20.437 | 0.653 | 4.183 | 58.245 | ||||||||||
P值 | 0.510 | 0.000 | 0.419 | 0.041 | 0.000 |
组别 | 例数 | 新生儿性别 | 孕产妇年龄 | 孕周 | 孕前吸烟史/[例(%)] | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
男/ [例(%)] | 女/ [例(%)] | <30岁/ [例(%)] | ≥30岁/ [例(%)] | <37周/ [例(%)] | ≥37周/ [例(%)] | ||||||||||
宫内感染组 | 44 | 26(59.09) | 18(40.91) | 24(54.55) | 20(45.45) | 25(56.82) | 19(43.18) | 5(11.36) | |||||||
无宫内感染组 | 87 | 50(57.47) | 37(42.53) | 46(52.87) | 41(47.13) | 48(55.17) | 39(44.83) | 5(5.75) | |||||||
χ2值 | 0.031 | 0.033 | 0.032 | 1.307 | |||||||||||
P值 | 0.859 | 0.856 | 0.858 | 0.253 | |||||||||||
组别 | 孕前饮酒史/[例(%)] | 孕前3个月感冒史/[例(%)] | 分娩方式 | 孕前体重指数 | 胎盘HBsAg阳性/[例(%)] | ||||||||||
顺产/[例(%)] | 剖宫产/[例(%)] | ≤24 kg/m2/[例(%)] | >24 kg/m2/[例(%)] | ||||||||||||
宫内感染组 | 8(18.18) | 18(40.91) | 29(65.91) | 15(34.09) | 24(54.55) | 20(45.45) | 36(81.82) | ||||||||
无宫内感染组 | 12(13.79) | 7(8.05) | 51(58.62) | 36(41.38) | 63(72.41) | 24(27.59) | 12(13.79) | ||||||||
χ2值 | 0.435 | 20.437 | 0.653 | 4.183 | 58.245 | ||||||||||
P值 | 0.510 | 0.000 | 0.419 | 0.041 | 0.000 |
危险因素 | β值 | 标准误 | Wald值 | P值 | 比值比值(95%可信区间) |
---|---|---|---|---|---|
孕前3个月感冒 | 0.228 | 2.667 | 5.203 | 0.010 | 1.256(1.045~4.193) |
孕前体重指数>24 kg/m2 | 0.472 | 3.156 | 6.280 | 0.002 | 1.603(1.235~7.039) |
胎盘HBsAg阳性 | 0.781 | 2.794 | 8.088 | 0.000 | 2.184(1.357~4.389) |
rs9275572位点GG基因型 | 0.551 | 3.110 | 12.355 | 0.000 | 1.735(1.243~5.231) |
rs9275319位点GG基因型 | 0.913 | 2.483 | 14.209 | 0.000 | 2.493(1.835~6.156) |
危险因素 | β值 | 标准误 | Wald值 | P值 | 比值比值(95%可信区间) |
---|---|---|---|---|---|
孕前3个月感冒 | 0.228 | 2.667 | 5.203 | 0.010 | 1.256(1.045~4.193) |
孕前体重指数>24 kg/m2 | 0.472 | 3.156 | 6.280 | 0.002 | 1.603(1.235~7.039) |
胎盘HBsAg阳性 | 0.781 | 2.794 | 8.088 | 0.000 | 2.184(1.357~4.389) |
rs9275572位点GG基因型 | 0.551 | 3.110 | 12.355 | 0.000 | 1.735(1.243~5.231) |
rs9275319位点GG基因型 | 0.913 | 2.483 | 14.209 | 0.000 | 2.493(1.835~6.156) |
1. | 侯思慧, 李青岭, 胡筠, 等. HLA-DQ遗传多态性与乙肝病毒感染结局相关[J]. 基础医学与临床, 2015, 35(7):873-878. |
2. |
刘洋铭, 饶海英, 漆洪波. 美国母胎医学会“妊娠期乙型肝炎的筛查、治疗及垂直传播的预防指南”要点解读[J]. 中国实用妇科与产科杂志, 2016, 32(6):505-507.
DOI |
3. | 陈静, 李奎. 宫内感染的产时处理[J]. 中华围产医学杂志, 2017, 20(11):1. |
4. |
SHI X, WANG X, XU X, et al. Impact of HBV replication in peripheral blood mononuclear cell on HBV intrauterine transmission[J]. Front Med, 2017, 11(4):548-553.
DOI URL |
5. | 陈萍, 段灵, 李正峰. HBV孕妇新生儿宫内感染的影响因素研究[J]. 中华医院感染学杂志, 2018, 28(16):2446-2449. |
6. | 高晶晶, 王金梅, 周小平, 等. HBsAg阳性产妇HBV宫内感染的危险因素分析[J]. 湖南师范大学学报(医学版), 2019, 16(6):173-176. |
[1] | FAN Lieying. Research status and application prospects of biomarkers for membranous nephropathy [J]. Laboratory Medicine, 2023, 38(12): 1111-1114. |
[2] | SUN Lincheng, LI Jianfeng, CHENG Weili, JI Panyun. Roles of anti-PLA2R IgG4 antibody and PLA2R IgG4/IgG ratio in primary membranous nephropathy [J]. Laboratory Medicine, 2023, 38(12): 1115-1120. |
[3] | LIU Qingyang, YUAN Jianming, XIA Jinjun, JIANG Fengying, WANG Qiubo, WANG Xiaoming. CXCL9 as a potential diagnostic marker of rheumatoid arthritis based on GEO database and experimental verification [J]. Laboratory Medicine, 2023, 38(12): 1121-1129. |
[4] | YANG Xiao, LI Enling, WU Lixia, DAI Yingxin, WANG Zhiqing, HUANG Hao, ZHENG Bing. Influence of cytoplasmic antinuclear antibody on indirect immunofluorescence assay based antineutrophil cytoplasmic antibody determination [J]. Laboratory Medicine, 2023, 38(12): 1135-1140. |
[5] | XIANG Jin, LIU Aiping, HU Yao, WU Zhiyuan, CAO Guojun, GUAN Ming. ANA profiles in COVID-19 patients and influence of serum heat-inactivation on ANA determination [J]. Laboratory Medicine, 2023, 38(12): 1141-1146. |
[6] | CHENG Yu, XU Zhen, LU Liu, DING Menglei, YU Shanshan, ZONG Ming, FAN Lieying. Expression and risk factors of anti-ACE-2 antibody in serum of patients with COVID-19 [J]. Laboratory Medicine, 2023, 38(12): 1147-1152. |
[7] | . [J]. Laboratory Medicine, 2023, 38(12): 1153-1156. |
[8] | . [J]. Laboratory Medicine, 2023, 38(12): 1157-1159. |
[9] | WANG Hongling, LIU Mengna, BAI Ping, LIAO Huanjin. Risk factors of relapse following allogeneic hematopoietic stem cell transplantation in patients with acute myeloid leukemia [J]. Laboratory Medicine, 2023, 38(12): 1160-1166. |
[10] | YANG Xilan, WANG Jinyu, LIU Shuyu, ZHAN Yiyang, LIU Jing, JIA Jian. Correlation between hyperlipidemia and endothelial microparticles in elderly patients from Gulou Community in Nanjing [J]. Laboratory Medicine, 2023, 38(12): 1167-1172. |
[11] | DAI Fangfang, LU Xinxin, YU Yanhua, CHEN Ming, SUN Guizhen. Analysis of Mycobacterium infection in HIV/AIDS patients [J]. Laboratory Medicine, 2023, 38(12): 1173-1176. |
[12] | GU Yu, LIANG Xiaoyan, MA Shenghui, TONG Na, CHENG Mingyan, YAN Zejun. Expression and near-term prognostic predictive value of plasma biomarkers in chronic kidney disease patients with thromboembolism [J]. Laboratory Medicine, 2023, 38(12): 1177-1182. |
[13] | . [J]. Laboratory Medicine, 2023, 38(12): 1183-1185. |
[14] | . [J]. Laboratory Medicine, 2023, 38(12): 1186-1190. |
[15] | . [J]. Laboratory Medicine, 2023, 38(12): 1191-1194. |
Viewed | ||||||
Full text |
|
|||||
Abstract |
|
|||||