Abstract:

Objective To analyze the clinical symptom and laboratory examinations of a case of green neutrophil and monocyte inclusions with malaria pigment retrospectively,and to improve the understanding of this case. Methods Through the clinical and pathologic findings,including complete blood counts,C-reactive protein,biochemical examination,malaria parasite antigen test,malaria parasite morphological examination and oil red O staining,the clinical symptom and laboratory examinations' characteristics were analyzed combined with literatures. Results The patient presented with high fever and joint pain as the initial clinical symptoms. Platelet count was 12×10⁹/L,the percentage of neutrophil was 82.7%,and C-reactive protein was >200 mg/L,accompanied by liver and renal dysfunction. Plasmodium falciparum was detected on peripheral blood smear. Green inclusions and malaria pigment were found in neutrophils and monocytes at the later stage of treatment,and the oil red O staining of green inclusions was positive. Conclusions The presence of green inclusions and malaria pigment is an important indication for the prognosis of severe malaria,which should be warned to clinicians.

Key words: Plasmodium falciparum, Green inclusion, Malaria pigment