Analysis on the results of coagulation four parameters and D-dimer in healthy pregnant women in Lan

doi:10.3969/j.issn.1673-8640.2020.04.011

Abstract

Abstract:

Objective To analyze the results of coagulation four parameters and D-dimer（DD） in healthy pregnant women with different gestational weeks in Lanzhou,and to provide a reference for assessing the status of maternal coagulation. Methodse Retrospective analysis was performed in 7 802 pregnant women and 168 non-pregnant women. According to different gestational weeks,7 802 pregnant women were classified into early pregnancy group,middle pregnancy group and late pregnancy group. Prothrombin time（PT）,activated partial thromboplastin time（APTT）,thrombin time（TT）,fibrinogen（Fib） and DD were determined. Results With the progress of gestational weeks,PT,APTT and TT in pregnant women were gradually shortened,and Fib and DD were gradually increased. Compared with pregnant groups,Fib and DD had statistical significance in non-pregnant group（P<0.01）. Conclusions The reference of PT,APTT,TT,Fib and DD for each pregnancy stage in Lanzhou has been established,which improves the application of maternal coagulation function determinations in clinical diagnosis.

Key words: D-dimer, Coagulation function, Reference interval, Pregnancy

CLC Number:

R446.1

zhou YE Ping, DONG Xuemei, ZHANG Chong, DU Xiaozhong. Analysis on the results of coagulation four parameters and D-dimer in healthy pregnant women in Lan[J]. Laboratory Medicine, 2020, 35(4): 334-337.

Figures/Tables 2

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组别	例数	PT/s	APTT/s	TT/s	Fib/（g/L）	DD/（mg/L）
非孕对照组	168	10.00~13.80	21.22~39.0	15.80~24.00	1.35~3.88	0.20
早孕组	535	9.90~13.30	20.70~35.88	15.30~23.60	1.90~4.32	1.15
中孕组	2 979	9.60~13.00	19.80~33.76	14.90~19.80	2.50~4.79	2.74
晚孕组	4 288	9.50~12.80	19.58~33.30	14.8~19.36	2.61~5.14	4.64

组别	例数	PT/s	APTT/s	TT/s	Fib/（g/L）	DD/（mg/L）
非孕对照组	168	10.00~13.80	21.22~39.0	15.80~24.00	1.35~3.88	0.20
早孕组	535	9.90~13.30	20.70~35.88	15.30~23.60	1.90~4.32	1.15
中孕组	2 979	9.60~13.00	19.80~33.76	14.90~19.80	2.50~4.79	2.74
晚孕组	4 288	9.50~12.80	19.58~33.30	14.8~19.36	2.61~5.14	4.64

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