Laboratory Medicine ›› 2019, Vol. 34 ›› Issue (12): 1145-1146.DOI: 10.3969/j.issn.1673-8640.2019.12.018
Previous Articles Next Articles
Received:2019-02-21
Online:2019-12-30
Published:2020-01-03
CLC Number:
Add to citation manager EndNote|Ris|BibTeX
URL: https://www.shjyyx.com/EN/10.3969/j.issn.1673-8640.2019.12.018
| 组别 | 例数 | 抗CCP抗体 | GPI抗原 | AKA | |||||
|---|---|---|---|---|---|---|---|---|---|
| 阳性（例） | 阳性率（%） | 阳性（例） | 阳性率（%） | 阳性（例） | 阳性率（%） | ||||
| RA组 | 80 | 6 | 7.50* | 63 | 78.75*# | 57 | 71.25*# | ||
| 非RA组 | 80 | 5 | 6.25* | 15 | 18.75* | 18 | 22.50* | ||
| 正常对照组 | 80 | 0 | 0.00 | 1 | 1.25 | 5 | 6.25 | ||
| 组别 | 例数 | 抗CCP抗体 | GPI抗原 | AKA | |||||
|---|---|---|---|---|---|---|---|---|---|
| 阳性（例） | 阳性率（%） | 阳性（例） | 阳性率（%） | 阳性（例） | 阳性率（%） | ||||
| RA组 | 80 | 6 | 7.50* | 63 | 78.75*# | 57 | 71.25*# | ||
| 非RA组 | 80 | 5 | 6.25* | 15 | 18.75* | 18 | 22.50* | ||
| 正常对照组 | 80 | 0 | 0.00 | 1 | 1.25 | 5 | 6.25 | ||
| 项目 | 准确性 | 特异性 | 敏感性 |
|---|---|---|---|
| 抗CCP抗体 | 91.3 | 96.9 | 80.0 |
| GPI抗原 | 62.5 | 54.4 | 78.8 |
| AKA | 66.7 | 64.4 | 71.3 |
| 抗CCP抗体+ GPI抗原 | 81.7 | 52.5 | 96.3 |
| 抗CCP抗体+AKA | 80.4 | 48.8 | 96.3 |
| GPI抗原+AKA | 70.0 | 43.8 | 83.1 |
| 抗CCP抗体+ GPI抗原+AKA | 83.8 | 56.3 | 97.5 |
| 项目 | 准确性 | 特异性 | 敏感性 |
|---|---|---|---|
| 抗CCP抗体 | 91.3 | 96.9 | 80.0 |
| GPI抗原 | 62.5 | 54.4 | 78.8 |
| AKA | 66.7 | 64.4 | 71.3 |
| 抗CCP抗体+ GPI抗原 | 81.7 | 52.5 | 96.3 |
| 抗CCP抗体+AKA | 80.4 | 48.8 | 96.3 |
| GPI抗原+AKA | 70.0 | 43.8 | 83.1 |
| 抗CCP抗体+ GPI抗原+AKA | 83.8 | 56.3 | 97.5 |
| [1] | 黄文辉,陈瑞林,曾颖瑜. CCP抗体、AKA和GPI抗原对类风湿性关节炎的诊断价值[J]. 广东医学,2010,31(14):1830-1832. |
| [2] | 杨梅花,王向红,冯忠军,等. RA患者血清中RF、CCP抗体、GPI抗原以及AKA检测的临床意义[J]. 热带医学杂志,2016,16(3):346-348. |
| [3] | 徐婧,刘婧,朱雷,等. 葡萄糖-6-磷酸异构酶水平测定与类风湿关节炎早期诊断[J]. 北京大学学报(医学版), 2016,48(6):942-946. |
| [4] | 董慧芳,薛海华. 抗CCP抗体、AKA、RF、GPI及RA33联合检测在类风湿关节炎的临床意义[J]. 中国冶金工业医学杂志,2016,33(3):291-292. |
| [5] | LAKOS G,SOÓS L,FEKETE A,et al. Anti-cyclic citrullinated peptide antibody isotypes in rheumatoid arthritis:association with disease duration,rheumatoid factor production and the presence of shared epitope[J]. Clin Exp Rheumatol,2008,26(2):253-260. |
| [6] | 张琼,罗以勤,汪元,等. 4种血清标志物在类风湿关节炎的诊断、疾病活动度的判断及骨侵蚀的预测的应用价值[J]. 安徽医科大学学报,2015,50(12):1791-1794. |
| [7] | 吴庆军,潘童,邓垂文,等. 血清葡萄糖6-磷酸异构酶抗原、类风湿因子和第2代抗环瓜氨酸肽抗体对类风湿关节炎诊断价值的比较[J]. 中华临床免疫和变态反应杂志,2013,7(2):115-119. |
| [1] | FAN Lieying. Research status and application prospects of biomarkers for membranous nephropathy [J]. Laboratory Medicine, 2023, 38(12): 1111-1114. |
| [2] | SUN Lincheng, LI Jianfeng, CHENG Weili, JI Panyun. Roles of anti-PLA2R IgG4 antibody and PLA2R IgG4/IgG ratio in primary membranous nephropathy [J]. Laboratory Medicine, 2023, 38(12): 1115-1120. |
| [3] | LIU Qingyang, YUAN Jianming, XIA Jinjun, JIANG Fengying, WANG Qiubo, WANG Xiaoming. CXCL9 as a potential diagnostic marker of rheumatoid arthritis based on GEO database and experimental verification [J]. Laboratory Medicine, 2023, 38(12): 1121-1129. |
| [4] | YANG Xiao, LI Enling, WU Lixia, DAI Yingxin, WANG Zhiqing, HUANG Hao, ZHENG Bing. Influence of cytoplasmic antinuclear antibody on indirect immunofluorescence assay based antineutrophil cytoplasmic antibody determination [J]. Laboratory Medicine, 2023, 38(12): 1135-1140. |
| [5] | XIANG Jin, LIU Aiping, HU Yao, WU Zhiyuan, CAO Guojun, GUAN Ming. ANA profiles in COVID-19 patients and influence of serum heat-inactivation on ANA determination [J]. Laboratory Medicine, 2023, 38(12): 1141-1146. |
| [6] | CHENG Yu, XU Zhen, LU Liu, DING Menglei, YU Shanshan, ZONG Ming, FAN Lieying. Expression and risk factors of anti-ACE-2 antibody in serum of patients with COVID-19 [J]. Laboratory Medicine, 2023, 38(12): 1147-1152. |
| [7] | . [J]. Laboratory Medicine, 2023, 38(12): 1153-1156. |
| [8] | . [J]. Laboratory Medicine, 2023, 38(12): 1157-1159. |
| [9] | WANG Hongling, LIU Mengna, BAI Ping, LIAO Huanjin. Risk factors of relapse following allogeneic hematopoietic stem cell transplantation in patients with acute myeloid leukemia [J]. Laboratory Medicine, 2023, 38(12): 1160-1166. |
| [10] | YANG Xilan, WANG Jinyu, LIU Shuyu, ZHAN Yiyang, LIU Jing, JIA Jian. Correlation between hyperlipidemia and endothelial microparticles in elderly patients from Gulou Community in Nanjing [J]. Laboratory Medicine, 2023, 38(12): 1167-1172. |
| [11] | DAI Fangfang, LU Xinxin, YU Yanhua, CHEN Ming, SUN Guizhen. Analysis of Mycobacterium infection in HIV/AIDS patients [J]. Laboratory Medicine, 2023, 38(12): 1173-1176. |
| [12] | GU Yu, LIANG Xiaoyan, MA Shenghui, TONG Na, CHENG Mingyan, YAN Zejun. Expression and near-term prognostic predictive value of plasma biomarkers in chronic kidney disease patients with thromboembolism [J]. Laboratory Medicine, 2023, 38(12): 1177-1182. |
| [13] | . [J]. Laboratory Medicine, 2023, 38(12): 1183-1185. |
| [14] | . [J]. Laboratory Medicine, 2023, 38(12): 1186-1190. |
| [15] | . [J]. Laboratory Medicine, 2023, 38(12): 1191-1194. |
| Viewed | ||||||
|
Full text |
|
|||||
|
Abstract |
|
|||||
