Laboratory Medicine ›› 2019, Vol. 34 ›› Issue (1): 1-7.DOI: 10.3969/j.issn.1673-8640.2019.01.001

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Clinical mass spectrometry:applications in clinical laboratories

Yan Victoria Zhang(), Thomas Jackson   

  1. Department of Pathology and Laboratory Medicine,University of Rochester Medical Center,Rochester 14642,USA
  • Received:2017-10-11 Online:2019-01-30 Published:2019-01-29

Abstract:

Mass spectrometry has demonstrated great utility and potential in clinical applications due to its unique advantages over traditional methods. The current applications are categorized into 3 different instrument platforms and technologies,including tripe quadruple mass spectrometry,time-of-flight mass spectrometry(TOF-MS) and inductively coupled plasma mass spectrometry(ICP-MS). This review is intended to provide an overview of determination items based on mass spectrometry in clinical laboratories and to focus on how technologies best support clinical needs. Furthermore,this review discusses the emerging applications of mass spectrometry in clinical laboratories to provide insights into the application of mass spectrometry in healthcare to better serve patient needs in the near future.

Key words: Mass spectrometry, Tripe quadruple mass spectrometry, Time-of-flight mass spectrometry, Inductively coupled plasma mass spectrometry, Clinical Laboratory, Determination item

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