Laboratory Medicine ›› 2018, Vol. 33 ›› Issue (4): 321-323.DOI: 10.3969/j.issn.1673-8640.2018.04.0010
• Orginal Article • Previous Articles Next Articles
Received:
2017-02-22
Online:
2018-04-30
Published:
2018-04-26
CLC Number:
Add to citation manager EndNote|Ris|BibTeX
URL: https://www.shjyyx.com/EN/10.3969/j.issn.1673-8640.2018.04.0010
组别 | 例数 | PLT(×109/L) | MPV(fL) | PDW(%) |
---|---|---|---|---|
CHB组 | 55 | 152.98±54.94** | 11.98±1.22** | 15.05±2.84** |
低载量组 | 20 | 156.10±65.06** | 11.73±0.95** | 14.84±2.53* |
中载量组 | 30 | 152.50±54.26** | 12.02±1.30** | 15.04±3.08* |
高载量组 | 15 | 149.40±43.30** | 12.27±1.43** | 15.36±3.07* |
正常对照组 | 50 | 228.70±56.09 | 10.49±1.48 | 13.13±3.13 |
组别 | 例数 | PLT(×109/L) | MPV(fL) | PDW(%) |
---|---|---|---|---|
CHB组 | 55 | 152.98±54.94** | 11.98±1.22** | 15.05±2.84** |
低载量组 | 20 | 156.10±65.06** | 11.73±0.95** | 14.84±2.53* |
中载量组 | 30 | 152.50±54.26** | 12.02±1.30** | 15.04±3.08* |
高载量组 | 15 | 149.40±43.30** | 12.27±1.43** | 15.36±3.07* |
正常对照组 | 50 | 228.70±56.09 | 10.49±1.48 | 13.13±3.13 |
组别 | 例数 | AST(U/L) | APRI |
---|---|---|---|
CHB组 | 55 | 79.00(46.00~234.00)* | 0.71(0.32~1.58)* |
低载量组 | 20 | 50.50(30.25~121.00)* | 0.50(0.22~1.00)* |
中载量组 | 20 | 101.50(54.75~233.50)* | 0.99(0.39~1.65)* |
高载量组 | 15 | 83.00(59.00~427.00)* | 0.82(0.32~1.83)* |
正常对照组 | 50 | 22.00(18.75~75.00) | 0.09(0.08~0.13) |
组别 | 例数 | AST(U/L) | APRI |
---|---|---|---|
CHB组 | 55 | 79.00(46.00~234.00)* | 0.71(0.32~1.58)* |
低载量组 | 20 | 50.50(30.25~121.00)* | 0.50(0.22~1.00)* |
中载量组 | 20 | 101.50(54.75~233.50)* | 0.99(0.39~1.65)* |
高载量组 | 15 | 83.00(59.00~427.00)* | 0.82(0.32~1.83)* |
正常对照组 | 50 | 22.00(18.75~75.00) | 0.09(0.08~0.13) |
[1] | GANEM D,PRINCE A M.Hepatitis B virus infection-natural history and clinical consequences[J]. N Engl J Med,2004,350(11):1118-1129. |
[2] | World Health Organization. Hepatitis B [EB/OL]. (2016-04-01)[2017-02-01]. . |
[3] | LU F M,ZHUANG H.Management of hepatitis B in China[J]. Chin Med J(Engl),2009,122(1):3-4. |
[4] | CHEN C J,YANG H I,SU J,et al.Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level[J]. JAMA,2006,295(1):65-73. |
[5] | ILOEJE U H,YANG H I,SU J,et al.Predicting cirrhosis risk based on the level of circulating hepatitis B viral load[J]. Gastroenterology,2006,130(3):678-686. |
[6] | 赖娅芳,杨岩,盛慧萍. 慢性乙型肝炎患者血清中IFN-γ、IL-10、TGF-β1水平与 HBV-DNA 载量的关系[J]. 宁夏医科大学学报,2010,32(2):211-213. |
[7] | 牛继华,曹辉,侯彦强. 乙型肝炎病毒DNA载量与血小板参数相关性分析[J]. 国际检验医学杂志,2016,37(2):280. |
[8] | 李双杰,覃小梅,范宸颖,等. 慢性乙型肝炎患儿HBV DNA载量与肝脏病理、肝功能、肝纤维化血清学指标的相关性分析[J]. 临床肝胆病杂志,2016,32(3):472-475. |
[9] | WAI C T,GREENSON J K,FONTANA R J,et al.A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C[J]. Hepatology,2003,38(2):518-526. |
[10] | FORNS X,AMPURDANÈS S,LLOVET J M,et al. Identification of chronic hepatitis C patients without hepatic fibrosis by a simple predictive model[J]. Hepatology,2002,36(4 Pt 1):986-992. |
[11] | IMBERT-BISMUT F,RATZIV V,PIERONI L,et al.Biochemical markers of liver fibrosis in patients with hepatitis C virus infection:a prospective study[J]. Lancet,2001,357(9262):1069-1075. |
[12] | KODA M,MATUNAGA Y,KAWAKAMI M,et al.FibroIndex:a practical index for predicting significant fibrosis in patients with chronic hepatitis C[J]. Hepatology,2007,45(2):297-306. |
[13] | LEE C M,LEUNG T K,WANG H J,et al.Evaluation of the effect of partial splentic embolization on platelet values for liver cirrhosis patients with thrombocytopenia[J]. World J Gastroenterol,2007,13(4):619-622. |
[14] | LAFFI G,MARRA F,GRESELE P,et al.Evidence for a storage pool defect in platelets from cirrhotic patients with defective aggregation[J]. Gastroenterology,1992,103(2):641-646. |
[15] | 欧宏杰,潘业,刘家俊,等. 慢性乙型肝炎患者外周血小板参数与肝脏组织病理的相关性分析[J]. 肝脏,2016,21(11):915-919. |
[16] | 都泓莲,彭颖,李烨,等. 慢性乙型肝炎患者血清肝纤维化指标与APRI指数及PLT的相关研究[J]. 检验医学与临床,2017,14(3):357-360. |
[17] | 高改云,李海中,樊宏伟,等. 乙肝患者血小板指标及生长激素-胰岛素样生长因子轴的变化观察[J]. 中华医院感染学杂志,2016,26(23):5348-5350. |
[18] | FELD J J,WONG D K,HEATHCOTE E J.Endpoints of therapy in chronic hepatitis B[J]. Hepatology,2009,49(5 Suppl):S96-S102. |
[19] | 冼永超,徐茹,杨景毅,等. 慢性乙型肝炎患者血清HBV-DNA 载量与肝组织病理的关系[J]. 中国临床医学,2007,14(3):337-338. |
[20] | LIN Z H,XIN Y N,DONG Q J,et al.Performance of the aspartate aminotransferase-to-platelet ratio index for the staging of hepatitis C-related fibrosis:an updated meta-analysis[J]. Hepatology,2011,53(3):726-736. |
[21] | GÜZELBULUT F,SEZIKLI M,AKKAN-CETINKAYA Z,et al. AST-platelet ratio index in the prediction of significant fibrosis and cirrhosis in patients with chronic hepatitis B[J]. Turk J Gastroenterol,2012,23(4):353-358. |
[1] | FAN Lieying. Research status and application prospects of biomarkers for membranous nephropathy [J]. Laboratory Medicine, 2023, 38(12): 1111-1114. |
[2] | SUN Lincheng, LI Jianfeng, CHENG Weili, JI Panyun. Roles of anti-PLA2R IgG4 antibody and PLA2R IgG4/IgG ratio in primary membranous nephropathy [J]. Laboratory Medicine, 2023, 38(12): 1115-1120. |
[3] | LIU Qingyang, YUAN Jianming, XIA Jinjun, JIANG Fengying, WANG Qiubo, WANG Xiaoming. CXCL9 as a potential diagnostic marker of rheumatoid arthritis based on GEO database and experimental verification [J]. Laboratory Medicine, 2023, 38(12): 1121-1129. |
[4] | YANG Xiao, LI Enling, WU Lixia, DAI Yingxin, WANG Zhiqing, HUANG Hao, ZHENG Bing. Influence of cytoplasmic antinuclear antibody on indirect immunofluorescence assay based antineutrophil cytoplasmic antibody determination [J]. Laboratory Medicine, 2023, 38(12): 1135-1140. |
[5] | XIANG Jin, LIU Aiping, HU Yao, WU Zhiyuan, CAO Guojun, GUAN Ming. ANA profiles in COVID-19 patients and influence of serum heat-inactivation on ANA determination [J]. Laboratory Medicine, 2023, 38(12): 1141-1146. |
[6] | CHENG Yu, XU Zhen, LU Liu, DING Menglei, YU Shanshan, ZONG Ming, FAN Lieying. Expression and risk factors of anti-ACE-2 antibody in serum of patients with COVID-19 [J]. Laboratory Medicine, 2023, 38(12): 1147-1152. |
[7] | . [J]. Laboratory Medicine, 2023, 38(12): 1153-1156. |
[8] | . [J]. Laboratory Medicine, 2023, 38(12): 1157-1159. |
[9] | WANG Hongling, LIU Mengna, BAI Ping, LIAO Huanjin. Risk factors of relapse following allogeneic hematopoietic stem cell transplantation in patients with acute myeloid leukemia [J]. Laboratory Medicine, 2023, 38(12): 1160-1166. |
[10] | YANG Xilan, WANG Jinyu, LIU Shuyu, ZHAN Yiyang, LIU Jing, JIA Jian. Correlation between hyperlipidemia and endothelial microparticles in elderly patients from Gulou Community in Nanjing [J]. Laboratory Medicine, 2023, 38(12): 1167-1172. |
[11] | DAI Fangfang, LU Xinxin, YU Yanhua, CHEN Ming, SUN Guizhen. Analysis of Mycobacterium infection in HIV/AIDS patients [J]. Laboratory Medicine, 2023, 38(12): 1173-1176. |
[12] | GU Yu, LIANG Xiaoyan, MA Shenghui, TONG Na, CHENG Mingyan, YAN Zejun. Expression and near-term prognostic predictive value of plasma biomarkers in chronic kidney disease patients with thromboembolism [J]. Laboratory Medicine, 2023, 38(12): 1177-1182. |
[13] | . [J]. Laboratory Medicine, 2023, 38(12): 1183-1185. |
[14] | . [J]. Laboratory Medicine, 2023, 38(12): 1186-1190. |
[15] | . [J]. Laboratory Medicine, 2023, 38(12): 1191-1194. |
Viewed | ||||||
Full text |
|
|||||
Abstract |
|
|||||