›› 2014, Vol. 29 ›› Issue (10): 989-991.DOI: 10.3969/j.issn.1673-8640.2014.10.001

• Orginal Article •     Next Articles

Investigation on the application significance on the combined detection of Hcy and RDW CV in the diagnosis of acute myocardial infarction

LIU Yijun1, LIU Hongliang2, XU Hong   

  1. 1.Department of Clinical Laboratory, Lianshui People's Hospital, Jiangsu Lianshui 223400, China;
    2.Department of Cardiology, Lianshui People's Hospital, Jiangsu Lianshui 223400, China
  • Received:2014-01-07 Online:2014-10-30 Published:2014-10-22

Abstract: Objective To investigate the clinical significance of the homocysteine (Hcy) and red blood cell distribution width coefficient of variation (RDW CV) combined detection in the diagnosis of acute myocardial infarction (AMI). Methods A total of 55 patients with AMI and 60 patients with pneumonia were enrolled, and 60 healthy subjects were enrolled as control group. The levels of Hcy and RDW CV were determined, and the results were compared. Resutls In AMI group, Hcy and RDW CV were significantly higher than those of pneumonia and control groups (P<0.05). The sensitivity of the combined detection of Hcy and RDW CV in the diagnosis of AMI was 92.0%, the specificity was 86.1%, which were higher than those of the single detections of Hcy and RDW CV (82.6%, 72.8% and 80.0%, 75.3%) (P<0 05). Conclusions The combined detection of Hcy and RDW CV can significantly improve the sensitivity and specificity in the diagnosis of AMI.

Key words: Homocysteine, Red blood cell distribution width coefficient of variation, Acute myocardial infarction, Combined detection, Sensitivity, Specificity

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