›› 2014, Vol. 29 ›› Issue (3): 202-208.DOI: 10.3969/j.issn.1673-8640.2014.03.002

• Orginal Article • Previous Articles     Next Articles

Evolutions in half a century: the course of change and development of current molecular diagnostics techniques

WU Zhiyuan,ZHANG Chen,GUAN Ming.   

  1. Huashan Hospital,Fudan University,Shanghai 200040,China
  • Received:2013-07-15 Online:2014-03-30 Published:2014-04-19

Abstract:

Molecular diagnostics techniques uses molecular biology techniques to analyze the nucleotide acid biomarkers of humen or pathogens,and to assist the clinical diagnosis of diseases. Since the innovation of liquid hybridization,molecular diagnostics has witness its rapid development for over half a century. Here we will assort the common molecular diagnostics procedures according to their methodological origins,so as to review the evolution of current clinical techniques,and to get a technical perspective on the development of molecular diagnostics.

Key words: Molecular diagnostics, Molecular hybridization, Nucleotide sequence, Molecular conformation variation, Polymerase chain reaction

CLC Number: